| Question | Answer |
| Schedule I | High Abuse Potential
No Recognized Medical Use
Heroin/LSD/Mescaline |
| Schedule II | Written Prescription Required
High Abuse Potential
Codeine/Morphine/Meperidine
Amphetamines/Phenmetrazine |
| Schedule III | High Abuse Potential
Prescription Required
Opiates/Stimulants/Depressants/Anabolic Steroids |
| Schedule IV | Prescription Required
Low Abuse Potential
Opiates/Stimulants/Depressants |
| Schedule V | Dispensed as any non-opiate Prescription
Low Abuse Potential |
| Assay | Test that determines the amount and purity of a drug |
| Bioequivalent | Relative therapeutic effectiveness of chemically equivalent drugs |
| Drug Absorption | Dependent on:
1.Solubility of drug
2.Concentration
3.Ph of drug
4.Site of absorption
5.Absorption area of site
6.Blood supply to area
7.Bioavailability |
| Distribution | Affected by:
1.Cardiovascular function
2.Regional blood flow
3.Drug storage reservoirs
4.Physiological barriers |
| Biotransformation | Name given to the metabolism of drugs
Has one of two effects on drugs:
1.transforms the drug into a more or less active metabolite
2.Makes the drug more water soluble to facilitate excretion |
| First Pass Effect | Process by which enteral drugs are absorbed via the GI track and through the liver, partially or completely inactivating the drug. |
| Elimination | Process of eliminating the drugs
Affected by:
1.Drugs Half-life
2.Accumulation of the drug
3.Clearance
4.Onset, Peak and Duration |
| Half-Life | Time required for the total amount of a drug to be diminished by one-half. |
| Accumulation | Through re-administration of maintenance doses, achieves a steady state of drug availability, although fluctuates within a given range |
| Clearance | Refers to the removal of a drug from the body |
| Onset of action | Time when sufficient amount of a drug is absorbed and distributed to obtain therapeutic effects |
| Peak Concentration | As more drug is absorbed, more is distributed and available to obtain therapeutic effects - Peak Concentration |
| Duration of Action | Is the length of time that drug concentration is sufficient enough to produce the therapeutic effect |
| Affinity | The force of attraction between a drug and a receptor |
| Efficacy | The ability of a drug to cause the expected response |
