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Gene Expression
Protein synthesis + Gene expression
| Question | Answer |
|---|---|
| Anticodon | Three consecutive bases on the tRNA |
| Codon | Three consecutive bases on the mRNA |
| Deletion Mutation | A mutation on the DNA where a base(s) is removed, resulting in a frameshift. |
| DNA | Deoxyribonucleic acid, double stranded, helix shaped large molecule. A&T, G&C |
| Enzyme | A folded protein which acts as a biological catalyst to speed up the rate of chemical reactions inn an organism. |
| Frameshift | Change in bases that the ribosome reads |
| Gene | A segment of DNA that codes for a protein/feature |
| Gene expression | The process where the instructions on our DNA are converted into a functional protein, includes transcription, translation and protein folding. |
| Genotype | The genetic makeup of an organism for a feature |
| Insertion Mutation | A mutation on the DNA where a base(s) is added resulting in a frameshift |
| Metabolic pathway | A series of enzyme-controlled reactions where the product of a reaction is used as a substrate in the next. |
| Missense Mutation | A change of the base on the DNA which codes for a different amino acid. This may or may not alter the shape of the protein and therefore it's function. |
| mRNA | Messenger RNA. Made during transcription in the nucleus. Carries the instructions to the ribosome to make a polypeptide chain. Contains codons. |
| Mutagen | The environmental factor that causes mutations. (X-rays, radiation, alcohol) |
| Mutation | A permanent and random change in the base sequence of the DNA |
| Non-sense Mutation | A change of the base on the DNA which changes the instructions, so a STOP codon occurs in the wrong place. Protein shape and function is greatly effected. |
| Peptide Bond | The bond formed between two amino acids during translation. |
| Phenotype | The physical expression of a feature |
| Point Mutation | A change of only one or a few bases on the DNA |
| Protein | A substance made up of many amino acids joined together by peptide bonds to form a polypeptide chain, which gets folded into a functional protein (enzymes are a type of protein). |
| Redundancy | The fact that multiple codons code for more than one amino acid (eg CCU, CCC, CCA, CCG all code for Pro) |
| Ribosome (rRNA) | A cell organelle consisting of RNA. They bind mRNA and tRNA to synthesise polypeptides and proteins |
| RNA | Ribonucleic acid, Three types: mRNA, tRNA, rRNA, single stranded and shorter than DNA. Sugar is ribose. A&U, G&C. |
| Same-sense Mutation | A change on the base of the DNA where the bases still code for the same amino acid. This is due to the Redundancy of the genetic code. |
| Silent Mutation | A mutation that is neither favourable nor harmful, that remains in a population. |
| Start Codon | The start codon signals on the mRNA which initiates translation, always AUG. |
| Stop Codon | These 3 codons on the mRNA (UAA, UAG, UGA) do not code for an amino acid therefore telling the ribosome where to stop translation. |
| Substitution Mutation | A mutation where the base(s) on the DNA are swapped. |
| Transcription | The process by which DNA going to mRNA, occurs in the nucleus. Controlled by RNA polymerase. |
| Translation | The process by which mRNA going to polypeptide chain, occurs in the cytoplasm on the ribosome |
| Triplet | Three consecutive bases on the DNA. |
| Transfer RNA | Carries an amino acid to the ribosome. 3 bases on the tRNA = an anticodon |