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Gene Expression

Protein synthesis + Gene expression

QuestionAnswer
Anticodon Three consecutive bases on the tRNA
Codon Three consecutive bases on the mRNA
Deletion Mutation A mutation on the DNA where a base(s) is removed, resulting in a frameshift.
DNA Deoxyribonucleic acid, double stranded, helix shaped large molecule. A&T, G&C
Enzyme A folded protein which acts as a biological catalyst to speed up the rate of chemical reactions inn an organism.
Frameshift Change in bases that the ribosome reads
Gene A segment of DNA that codes for a protein/feature
Gene expression The process where the instructions on our DNA are converted into a functional protein, includes transcription, translation and protein folding.
Genotype The genetic makeup of an organism for a feature
Insertion Mutation A mutation on the DNA where a base(s) is added resulting in a frameshift
Metabolic pathway A series of enzyme-controlled reactions where the product of a reaction is used as a substrate in the next.
Missense Mutation A change of the base on the DNA which codes for a different amino acid. This may or may not alter the shape of the protein and therefore it's function.
mRNA Messenger RNA. Made during transcription in the nucleus. Carries the instructions to the ribosome to make a polypeptide chain. Contains codons.
Mutagen The environmental factor that causes mutations. (X-rays, radiation, alcohol)
Mutation A permanent and random change in the base sequence of the DNA
Non-sense Mutation A change of the base on the DNA which changes the instructions, so a STOP codon occurs in the wrong place. Protein shape and function is greatly effected.
Peptide Bond The bond formed between two amino acids during translation.
Phenotype The physical expression of a feature
Point Mutation A change of only one or a few bases on the DNA
Protein A substance made up of many amino acids joined together by peptide bonds to form a polypeptide chain, which gets folded into a functional protein (enzymes are a type of protein).
Redundancy The fact that multiple codons code for more than one amino acid (eg CCU, CCC, CCA, CCG all code for Pro)
Ribosome (rRNA) A cell organelle consisting of RNA. They bind mRNA and tRNA to synthesise polypeptides and proteins
RNA Ribonucleic acid, Three types: mRNA, tRNA, rRNA, single stranded and shorter than DNA. Sugar is ribose. A&U, G&C.
Same-sense Mutation A change on the base of the DNA where the bases still code for the same amino acid. This is due to the Redundancy of the genetic code.
Silent Mutation A mutation that is neither favourable nor harmful, that remains in a population.
Start Codon The start codon signals on the mRNA which initiates translation, always AUG.
Stop Codon These 3 codons on the mRNA (UAA, UAG, UGA) do not code for an amino acid therefore telling the ribosome where to stop translation.
Substitution Mutation A mutation where the base(s) on the DNA are swapped.
Transcription The process by which DNA going to mRNA, occurs in the nucleus. Controlled by RNA polymerase.
Translation The process by which mRNA going to polypeptide chain, occurs in the cytoplasm on the ribosome
Triplet Three consecutive bases on the DNA.
Transfer RNA Carries an amino acid to the ribosome. 3 bases on the tRNA = an anticodon
Created by: Mackenzie.
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