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Glycolysis steps
For each molecule, describe what happens to it in Glycolysis
Question | Answer |
---|---|
Glucose | Enters Glycolysis and is phosphorylated. 1 ATP is invested. Becomes Glucose 6-Phospate |
Glucose 6-Phosphate | Is modified by Phosphoglucoisomerase into Fructose 6-Phosphate |
Fructose 6-Phosphate | Is phosphorylated making it Fructose 1,6-diphosphate. One ATP is invested. |
Fructose 1,6-diphosphate | Is cleaved into two 3 carbon molecules each with one Phosphate group: Dihydroxyacetone Phosphate and Glyceraldehyde 3-phosphate. |
Dihydroxyacetone Phosphate | Gets converted into Glyceraldehyde 3-phosphate by an enzyme called isomerase so that it can enter the next phase of Glycolysis - the energy conserving stage. |
Glyceraldehyde 3-phosphate (2 Molecules) | Is oxydized - transfers H+ to NAD+. Obtains a high energy phosphate bond making it 1,3 diphosphoglyceric acid. (Remember! This rxn is X2!) |
1,3-diphosphoglyceric acid (2 Molecules) | The high energy phosphate bond is removed from the 1st Carbon - producing ATP. 3-phosphoglyceric acid remains. |
3-phosphoglyceric acid (2 molecules) | is modified by an enzyme that moves the P group to the 2nd carbon making 2-phosphoglyceric acid. |
2-phosphoglyceric acid (2 molecules) | loses a H20 molecule. The P group becomes a high energy bond - making Phosphoenolpyruvic Acid. |
Phosphoenolpyruvic Acid (2 molecules) | The high energy phosphate bond is broken and the P group is transferred to ADP making ATP. Pyruvic Acid is formed |
Pyruvic Acid (2 molecules) | Pyruvic Acid is free to enter the Krebs Cycle/Citric Acid Cycle. |
How many ATPs are used in glycolysis? | 2 |
How many ATPs are produced in glycolysis | 4 |
How many ATPs are NETTED in glycolysis? | 2 |
How many NADH are produced in glycolysis? | 2 |