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Review For Final
Chapter 13 and 16
| Term | Definition |
|---|---|
| Somatic cells | non-gamete cells that do not pass genetic material to offspring |
| Gametes | cells that pass on genetic material during sexual reproduction |
| Zygote | cell formed when egg and sperm fuse |
| Chromatin | DNA plus histones |
| Euchromatin | decondensed chromatin |
| Heterochromatin | condensed chromatin |
| Semi-conservative replication | both template strands form new DNA strands |
| Anti-parallel | daughter strands run opposite of parental strands (3′→5′ vs 5′→3′) |
| Replication origins | sites where DNA separates and replication begins |
| Helicase | enzyme that unwinds DNA |
| Single-stranded binding proteins | prevent separated DNA strands from re-pairing |
| Topoisomerase | stabilizes double-stranded DNA near origins |
| Replication forks | areas near replication origins where DNA is still double-stranded |
| DNA Polymerase | enzyme that adds new nucleotides to daughter strand |
| Primase | adds RNA primers to start synthesis |
| Leading strand | synthesized continuously |
| Lagging strand | synthesized in fragments (Okazaki fragments) |
| DNA Ligase | fuses Okazaki fragments |
| DNA Polymerase I | removes RNA primers |
| Mismatch | mistake in DNA sequence during replication |
| Nucleases | enzymes that remove mismatches |
| Mutagens | environmental factors that damage DNA |
| Point mutation | mutation of a single nucleotide |
| Nucleotide excision repair | removes thymine dimers from UV damage |