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DNA Replication

TermDefinition
topoisomerase catalyze transient breaks in DNA strands (swivel points)
helicase catalyze unwinding of parental DNA
primase synthesizes complementary strand (short RNA sequence)
RNA primer starting point for DNA synthesis
Okazaki fragments short discontinuous pieces found in lagging strand
polymerase III elongation & proofreading
polymerase I remove & replace primers
lagging strand synthesized in short discontinuous pieces
ligase connects Okazaki fragments on lagging strand
single-stranded DNA-binding proteins hold 2 strands of DNA separate during replication
clamp loading protein load sliding-clamp protein
sliding-clamp protein load polymerase onto primer & maintains its association w/ template
leading strand synthesizes continuous in 5'-3' direction
DNA polymerase catalyzes the joining on dNTPs
Created by: RJEstes
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