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Week 2 - Chapter 2

Drug Action and Handling

TermDefinition
Low Dose Effect Curve Measuring the response to the dose of the drug
Potency The amount of drug required to produce an effect
Efficacy Related to the maximal effect of a drug regardless of dose
Therapeutic Range Range between the dose causing the minimum effect and the dose causing the minimum adverse effect
Therapeutic Index Number that determines the safety of a drug
Efficacy The maximum intensity of effect or response that can be produced by a drug
Renal Kidney
Hepatic Liver
Biotransformation The body's way of changing a drug so that it can be more easily excreted by the kidneys
Tolerance The need for an increasingly larger dose of the drug to obtain the same effects as the original dose
Duration The length of a drug's effect
Half-Life The amount of time that passes for its concentration to fall to half (50%) of its original blood level
Median Effect Dose (ED50) The dose required to produce a desired clinical effect in 50% of test subjects; a low effective dose is preferred because it means less drug is needed to achieve desired effects
Lethal Dose (LD50) The amount of a substance that causes death in 50% of a test population; a lower LD means the substance is more toxic
Created by: Celrrose
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