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BIO EXAM 2
| Term | Definition |
|---|---|
| Crossing over occurs in | prophase 1 |
| Alfred Sturtevant | constructed 1st chromosomes map |
| Chiasmata | where crossing over occurs in meiosis 2 |
| Repulsion | dominant alleles on 1 homolog & recessive alleles on the other |
| coupling | both homologs has a dominant & recessive allele |
| p | frequency of A alleles in population |
| q | frequency of a alleles in population |
| p^2 | AA homozygotes frequency |
| q^2 | aa homozygotes frequency |
| 2pq | Aa heterozygotes frequency |
| Hardy Weinberg Equilibrium | freq remains constant unless affected by factors other than mendelian |
| Sewall Wright, R.A Fisher, J.BS. Haldane | population genetics "The new evolutionary synthesis" |
| Natural selection involves the violation of hardy weinbergs assumption | all genotypes equally likely to produce offspring |
| Mutation selection Balance | has harmful recessive allele |
| F. Griffith | discovered genetic transformation in streptococcus pneumonide |
| Oswald Avery | set out to identify the "transforming substance" |
| Avery, McClead, & McCarty | Found out DNA is the transforming substance not RNA |
| Hershey & Chase | Confirmed that DNA was the genetic material |
| Results of Hershey and Chase Experiment | 32P- radioactivity in pellets of cells 35S- radioactivity in supernatant |
| DNA has | phosphorus but no sulfur |
| Protein has | sulfur but little phosphorous |
| Watson and Crick | figured out DNA structure (double helix) |
| F. Chargaff | found base pairs (A=T and G=C) |
| Franklin and Wilkins | X-ray diffraction of DNA fibers that shows helical structure. |
| AT | has 2 H bonds |
| GC | has 3 H bonds |
| 5' to 3' | starts with phosphorous ends in OH |
| 3' to 5' | starts with OH and ends with phosphorous |