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Parasite/pathogen

Host manipulation

QuestionAnswer
Why manipulate? - extending parasite surival - castration of host to conserve energy spent on reproduction
Why manipulate? Gigantism Resources are strategically reallocated to invest into host body growth, maintenance and survival ensuring longer infective period for the parasite a means of ensuring storage of resources from the host for the parasite to use later
Why manipulate? Increasing transmission - improve host transmission - changing host behaviour and morphology
Transmission routs - manipulate your current host to ensure the next generation of parasites is released in an advantageous place - manipulate your host to ensure you reach your next intermediary
Changing host behaviour - transmission site ie. Cordyceps fungus Ants infected fall down a lot more Movement is less directional Death grip accompanied by muscle atrophy around the mouth
Changing host behaviour – finding the next intermediary e.g. Toxoplasma Behavioural changes associated with inflammation of the brain due to cysts
Changing host morphology - colouration and odour ie. land snails and certain ants
Changing host morphology - feminisation - Typically increases vertical transmission down the female line - Generally transmitted vertically by the female through eggs to the progeny – although horizontal transfer is possible
Wolbachia in nematodes, insects and crustaceans Wolbachia may kill or feminise males in the embryonic or larval stages or induce thelytokous parthenogenesis where virgin females produce daughters This alters sex ratios in the progeny in favour of females which ensures higher transmission rates
Wolbachia in nematodes, insects and crustaceans Cytoplasmic incompatibility also means infected females have a reproductive advantage over uninfected females
Cost of manipulation Nothing is free Development of manipulatory traits may come at the cost of another trait
Dinocampus coccinellae - parasitoid wasp of ladybirds - Females deposit a single egg inside the haemocoel of the host and larvae feeds on host tissue - Host is however not killed during larval development
Dinocampus coccinellae - parasitoid wasp of ladybirds - The larvae will emerge and spin a cocoon between the ladybirds legs - Wasp cocoons attended by manipulated but living hosts showed differences in predation and length of manipulation period impacted fecundity but not longevity
Liver fluke - Ants become infected when they eat parasite infested slime balls from snails - When in the ant most flukes infest the hemolymph but one individual migrates to the ants brain – the brain worm
Liver fluke - When the evening comes infected ants leave the colony and climb blades of grass waiting to be eaten by the definitive host - When day comes though infected ants that have not been consumed behave normally until evening again
The brain worm The brain worm however won’t develop into infectious stages – so wont benefit from manipulations
Created by: rose.coo
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