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lecture 13
Term | Definition |
---|---|
genetic drift | mechanism of evolution, specially in small populations |
genetic drift results from | random sampling error |
sampling error is higher with a | small sample |
drift reduces | genetic variation in population |
some alleles become | fixed in the population, while others disappear |
bottlenecks reduce | genetic variation |
bottleneck results in a | nonrepresentative set of alleles for subsequent populations |
rare alleles are most likely to be | lost during a bottleneck |
the probability of an allele making it through a bottleneck depends on | frequency of the allele before the bottleneck and the severity of the bottleneck |
founder effect | type of bottleneck resulting from small number of individuals colonizing a new, islotated habitat |
fitness | survival and reproductive success of an individual w a particular phenotype |
relative fitness (w) | contribution of individuals w one genotype compared w the average contribution of all individuals in the population |
components of fitness | survival to reproduce age, mating success, fecundity (offspring by females) |
average excess fitness | diff between relative contribution with one genotype and the avg fitness of population as a whole (remember formula) |
natural selection is more effective in | large population in bringing about change |
pleitropy | may constrain evolution, mutation in a single gene affects more than one phenotype trait |
antagonistic pleitropy | beneficial effects for one trait but detrimental effects for other traits |
experimental studies provide | important insights about selection |
negative selection | alleles that lower fitness experience |
positive selection | alleles that increases fitness experience |
some mutations increased and became fixed, while others | disappeared from the population |
additive alleles | homozygous conditions yields twice the phenotypic effect for the gene as compared with heterozygotes |
dominance | dominant alleles masks presence of recessive in heterozygote |
mutation rates | for any given gene are low |
many new mutations arise each | generation |
equilibrium frequency | reached thru a tug of war between negative selection s on alleles and new mutations, explains deleterious mutations in populations |
balancing selection | describes type of selection that favors more than one allele |
negative frequency-dependent selection | common phenotypes are selected against, rare phenotypes are favored |
heterozygote advantage | confers greater fitness than homozygotes |
heterozygote advantage and | sickle cell anemia |
inbreeding and the | hapsburg dynasty |
inbreeding coefficient | expected from a brother and sister |
inbreeding depression results in | reduced fitness |
high inbreeding tend sot be associated with | low infant survival rates |
rare recessive alleles are expressed in | homozygous state |
many organisms occupy ranges that | are discontinuous |
population subdivision (metapopulation) | depends on landscape and relative degree of individuals in the population (depending in population size) |
genetic drift creates | genetic distance between populations |
subdivision population show | distinct genetic structure |
Fst | is a measure of genetic distance between subpopulations |
gene flow can counteract the | loss of alleles due to drift |
amount of gene flow varies with the | range of movement of the organism |
humans alter population structure by constructing | barriers between populations |