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preg everything

sorry exam me

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menstruation~ Corpus luteum degenerates, reducing amount of progesterone, resulting in break down of endometrium lining.blood from broken down capillaires, mucous secretions & cell deebbris are lost through the vagina
Describe the influence of the hormones oestrogen and progesterone (both increased and decreased levels) on the endometrium Oestrogen – builds endometrium tissue (in uterus after menstruation) Progesterone – maintains endometrium tissue low levels of both cause period
Describe the influence of the hormones oestrogen and progesterone on the pituitary gland High enough level of oestrogen stimulates spike in LH & FSH  ovulation of most mature follicle, releasing less oestrogen high progesterone influences development of lining of uterus & inhibits releasee oof LH & FSH
Give some factors that are known to trigger stem cell differentiation Internal – cell gene External – chemicals secreted by other cells, physical contact with other cells, certain molecules in microenvironment
endoderm - epithelium of all internal organs germ layer inside
mesoderm - muscle tissue, connective tissue germ middle
ectoderm - hair, nails, receptor cells, nervous system germ outside
amnion - embryo membrane First membrane to develop. By 8th day of fertilization surrounds mebbryo & secretes amniotic fluid. – protect from injury (shoock absorber) maintain constant temp, allows free movement. Amnion ruptures at birth – water break
chorion Formed from outer cells of blastocyst & mesodermal cells. Surrounds embryo & other embryonic membrane. Main part of the foetal portion of the placenta
Describe the structure of the placenta in terms of foetal and maternal circulation Begins to develop as blastocyst impants. Chorionic villi develop grow into the endometrium. As they penetrate they are surrounded by mothers blood, but don’t miix. Exchange occurs through diffusion & active transport
Outline the major functions of the placenta endocrine - secrete hormones maintain preg excretory - transport nitrogenous waste tto mum kidney immune - transport antibodies nutritional - transport nutrients from mother to fetus blood respiratory - transport O to fetus, CO to mum
Outline the importance of protein, folic acid, calcium and vitamin A in the maternal diet during pregnancy Folic acid – normal cell division & manufacturing of protein, if nnott develop spina bifida & other nueral tube disorders Calcium – normal bone growth, teeth, heart, nerve & muscle deevelopment Vitamin a – normal growth of cells.
Outline the influence that alcohol can have on development during pregnancy Foetal alcohol syndrome (FAS) – lower birth weight, slow growth, small head, irregularities of face, defects of heart & other organs, malformed arms & legs, intellectual disabilities, behavioural problems
Outline the influence that smoking can have on development during pregnancy Lower birth weight, increased risk of miscarriage gastrointestinal problems respiratory problems & sudden infant death syndrome
Outline the influence that thalidomide can have on development during pregnancy Thalidomide: a teratogen that causes babies to be born with limb malformations. Effects day 28-42. Arms develop before legs and are more likely to be effected.
Describe how amniocentesis is used to obtain foetal cells for genetic analysis A needle, is inserted through the mother’s abdomen to take a small sample, ~ 10-20ml, of amniotic fluid from around the baby. Living cells from the foetus are floating in the fluid and can be examined for biochemical/chromosome defects
Describe how chorionic villus sampling (CVS) is used to obtain foetal cells for genetic analysis A needle, guided by ultrasound, is inserted through the mother’s abdomen to take a sample of chorionic villus cells from the placenta. This sample of foetal cells is then tested for missing, extra or abnormal chromosomes.
Outline the advantages of CVS over amniocentesis cvs - fetal tissue can be tested quicker
Outline the purpose and limitations of maternal blood tests Purpose: Tests for hormone concentrations (free B-hCG and PAPP-A). In a woman whose baby has a serious chromosome problem, the levels of these hormones will differ. Screens for: Down syndrome, Edwards syndrome, Patau syndrome, Turner syndrome
Describe how a sample of foetal blood is collected and then used to monitor foetal development The umbilical cord via percutaneous umbilical cord blood sampling (PUBS), where a needle is inserted through the abdominal wall and uterus into the umbilical vein.
Describe how and why the foetal liver is bypassed via the ductus venosus Ductus venosus: the foetal blood vessel that enables blood to bypass the liver. contains oxygen & nutrients Liver is bypassed as it isn’t fully functional until after birth
Describe how and why the foetal lungs are bypassed via the ductus arteriosus Lungs are bypassed as they are currently collapsed. most blood from right ventricles flows thrugh ductus arteriosus to aorta (instead of lungs)
Created by: procrast
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