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Bio Chapter 5
Membranes
Term | Definition |
---|---|
The 2 primary structural components of membranes | Phospholipids and proteins |
Phospholipid bilayer | the framework of the membrane, amphiapathic |
Phospholipid "head" | hydrophilic and faces outward |
Phospholipid "tail" | hydrophoobic and is on the inside of the phospholipid bilayer |
Fluid-mosaic model | describes the membrane as a mosaic of lipids, proteins, and carbohydrates |
Extracellular leaflet of the phospholipid bilayer | the half facing the outside of the cell and where glycolipids are found |
transmembrane proteins | span both leaflets on the membranes |
Peripheral membrane proteins | bonded covalently to amino acids |
integral proteins examples | transmembrane and lipid anchored proteins |
How does the length of non polar tails affect the phospholipid bilayer | Shorter tails make it more fluid |
How does the presence of double bonds affect the phospholipid bilayer | Double bonds makes it more fluid |
How does the presence of cholesterol affect the phospholipid bilayer | Stabilizes, When its colder the more stable the cells are, but when its warmer the cells will move |
plasma membrane characteristics | selectively permeable |
3 general ways of transport | simple diffusion, facilitated diffusion, active transport |
simple diffusion | movement of a solute down a gradient, High concentration to low concentration |
facilitated diffusion | movement down a gradient with the help of a transport protein, High concentration to low concentration |
Active transport | movement up a gradient with the help of a transport protein and energy (low concentration to high concentration |
small molecules diffuse ______ than larger molecules | faster |
polar molecules diffuse _____ than non polar molecules | slower |
Non charged molecules diffuse ______ than charged | faster |
Transmembrane gradient | is when the concentration of a solute is high on one side of a membrane than the other |
electrochemical gradient | is a dual gradient with both electrical and chemical components |
What happens when the surroundings of the membrane is isotonic | theres a same solute concentration inside and outside cell |
What happens when the surroundings of the membrane is Hypertonic | theres more solutes outside the cell |
What happens when the surroundings of the membrane is hypotonic | theres less solutes outside the cell |
The relationship between solutes and water | More solutes = less free water, Less solutes= More free water |
osmosis | is the movement of water across membranes to balance solute concentrations |
When water moves high to low concentration | osmosis |
transport proteins | are transmembrane proteins that provide passage for the movement of ions and hydrophilic molecules across membranes |
Channels in membrane transport | provide an open passage way that facilitates diffusion of polar molecules or ions |
regulatory signals | opens and closes channels |
Transporters | Carriers that bind solutes for transport |
Uniporter transporter | a single solute moves in one direction |
symporter transporter | two solutes moves in the same direction |
antiporter transporter | two solutes moves in opposite directions |
Active transporter | the movement of a solute against its gradient |
primary active transport | uses energy from ATP to transport |
secondary active transport | Uses pre-existing energy to transport |
Na+/K+ -ATPase | an antiporter that actively transports Na+ and K+ against their gradients using the energy from ATP hydrolysis |
__ Na+ are exported for every __ K+ imported into a cell | 3, 2 |
Cells invest up to ____ of energy into ion pumping | 70% |
intercellular channels | direct movement of substance between adjacent cells |
Gap junctions connects ______ | Animal cells |
Plasmodesmata connects ______ | plant cells |
gap junctions | a cluster of many connexons and provides passage of ions and small molecules |
Connexons | made of connexins that align into a channel |
Connexins | 6 membrane proteins that assemble connexons |
desmotubule | connects the smooth ER membranes membranes of adjacent cells |
endocytosis | the movement of large materials into the cell |
Exocytosis | the movement of large materials out of the cell |
Exocytosis functions | secretion of hormones (insulin), secretion of enzymes |
Endocytosis functions | uptake of vital nutrients (lipids), forming of root nodules, destroying bacteria (phagocytosis) |
receptor -mediated endocytosis | uses receptor proteins to bring in specific cargo |
Pinocytosis | brings fluid, good for cells to sample |
Phagocytosis | involves bringing of large particles like bacteria cells |
Anchoring junctions | link cells to each other or to the ECM |
Cell adhesion molecules (CAMS) examples | Cadherins and integrins |
Cadherins characteristics | links cells to cells |
integrins characterisitics | links cells to ECM |
Adherens junctions Connects what? Uses which CAM? Binds what? | connects cell to cell Uses cadherins bind to actin filaments |
Desmosomes Connects what? Uses which CAM? Binds what? | Connects cell to cell Uses cadherins binds to intermediate filaments |
Hemidesmosomes Connects what? Uses which CAM? Binds what? | connects cell to ECM Uses integrins Binds intermediate filaments |
Focal adhesions Connects what? Uses which CAM? Binds what? | Connects cell to ECM Uses integrins Binds Actin filaments |
tight junctions | form a tight seal between cells and prevent leakage |