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tumour invasion
Pathophysiology
| Question | Answer |
|---|---|
| What is the spread of cancer cells from one organ of the body to a non-adjacent organ | Metastasis |
| This 3 step theory describes the events during the invasion of extracellular matrix | Three step theory of invasion |
| When a tumor cell attaches to the extracellular matrix via laminin receptors | Step one of the three step theory of invasion |
| Degradation of the matrix by tumor cell proteases | Step two of the three step theory of invasion |
| Migration of the tumor cell through the basal membrane via attachment to fibronectin, formation of pseudopodia | Step three of the three step theory of invasion |