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Chemokines
| Question | Answer |
|---|---|
| chemokine | chemotactic cytokine |
| chemotaxin | attract and activate leukocytes |
| CXC chemokines | attract neutrophils and T cells |
| CC chemokines | attract a variety of leukocytes but not neutrophils |
| non-selective chemotaxins | complement, LTB4 |
| CCR5 antagonists | used in the treatment of HIV |
| CCR4 mAb | moglizumab |
| CXCR4 antagonist | balixafortide |
| chemoattractant | direct leukocyte movement |
| transmigration | movement of leukocyte towards chemotactic gradient |