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Chapter 16.1

DNA Structure

QuestionAnswer
grifith's experiment -used a pathogenic bacteria and a harmless bacteria on mice -pathogenic killed mice, harmless did not
what was found in grifith's experiment? -when heat-killed remains of pathogen mixed with living cells of harmless, mice died because some cells became pathogenic -transformation, identified by avery, macleod, and mccarty that it was change in phenotype and genotype due to foreign DNA
bacteriaphage a virus that infects bacteria
hershey and chase experiment determined that DNA was the genetic material -radioactive sulfur tag on protein, radioactivity found in solution because T2 phage did not inject protein -radioactive sulfar tag on DNA, radioactivity found in pelleet because DNA was injected by T2
chargaff's law -Base composition of DNA varies by species -In any species, that number of A and T bases are equal and number of C and G bases are equal
williams and franklin -used x-ray crystallography to produce picture of a DNA molecule -enabled Watson and Crik to deduce DNA was helical, width, height, and spacing of helix
DNA two long chains of nucleotides twisted into a double helix and joined by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine -built from 5'-3' end antiparallel to 3'-5'
DNA structure -5' = phosphate group with CH2 attached -3' = the next nucleotide attached/OH -complementary base pairing ensures uniform width of 3 nitrogenous bases
Created by: maddiemiller
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