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Exam 1-2
Genetics
| Term | Definition |
|---|---|
| multiplication method | for Punnett squares w/3 or more genes |
| forked-line method | for Punnett squares w/3 or more genes |
| loss-of function alleles | defective copies of genes |
| non-disease causing allele | normal protein |
| mutant allele | causes disease |
| wild-type allele | normal functioning allele |
| probability | number of times an event occurs / total number of events; the chance that the events will occur in the future |
| accuracy of probability | depends on sample size |
| random sampling error | large for small samples/ small for large samples |
| product rule | probability that two or more independent events will occur is equal to the product of their respective probabilities |
| binomial expansion equation | represents all of the possibilities for a given set of unordered events; P= (n!/x!(n-x)!)*p^x*q^(n-x) |
| factorial | product of all integers from n down to 1 |
| Chi Square test | statistical method to determine goodness of fit, how close the observed data are to those predicted from a hypothesis, does not prove a hypothesis is correct; x^2=sum(O-E)^2/E |
| P values | probabilities from a chi square test |
| low chi square values | high probability that the observed deviations could be due to random chance alone |
| high chi square values | low probability that the observed deviations are due to random chance alone |
| chi square- hypothesis rejected | probability is less that 0.05 |
| degrees of freedom | df=n-1, measure of the number of categories that are independent of each other |
Created by:
carleisapp
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