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U1 - KA2c - Proteins

What joins amino acids together to create a polypeptide? Peptide bonds
In which 5 ways do R groups differ from one another? Size, Shape, Charge, Hydrogen bonding capacity, chemical reactivity.
What are the four classifications of amino acids? Basic, acidic, polar and hydrophobic
Which amino acid groups are positively charged? Basic amino acids
Which amino acid groups are negatively charged? Acidic amino acids
If an amino acid has an -OH in their R group, this can be categorised as which amino acid? Polar
If an amino acid has an -NH2 in their R group, this can be categorised as which amino acid? Basic
If an amino acid has carbons and hydrogens in their R group, this can be categorised as which amino acid? Hydrophobic
If an amino acid has an -COOH in their R group, this can be categorised as which amino acid? Acidic
What determines protein structure The sequence of amino acids.
Which type of reaction causes a peptide bond to form? A condensation reaction
What is the byproduct of a condensation reaction? A water molecule
Define the primary structure of a protein. The sequence in which the amino acids are synthesised into a polypeptide.
Which bond stabilises the secondary structure of a protein? Hydrogen bonds
Where would you find hydrogen bonds? Along the backbone of the protein strand.
What are the three types of secondary protein structure? Alpha helix, beta pleated sheets, turns
Which type of beta pleated sheet has chains running in opposite directions? Anti-parallel beta pleated sheet.
Which bonding stabilises the tertiary structure of a protein? Ionic, London dispersal forces, disulfide bridges, hydrogen and hydrophobic
What is the quaternary structure of a protein? When multiple polypeptide subunits are joined together.
What is a non-protein component called? A prosthetic group
What is the definition of a prosthetic group? A non protein component that is essential for the proteins function.
What is the proteome? The entire set of proteins expressed by the genome.
Why is the proteome larger than the genome? Due to alternative RNA splicing
What do non-coding RNA genes code for? tRNA, rRNA and other RNA's that control the expression of other genes.
State a factor that can affect the specific proteins expressed in a cell. Metabolic activity of the cell, cellular stress, response to signalling molecules and diseased cells.
Created by: StNiniansHS
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