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BIO 121-01
Study Guide
Question | Answer |
---|---|
Helicase | Unwinds parental double helix at replication forks |
Single-strand binding protein | Bins to and stabilizes single-strand DNA until it is used as a stemplate |
Topoisomerase | Relives overwinding strain ahead of replication forks by breaking, swiveling, and rejoining DNA strands |
Primase | Synthesizes and RNA primer at 5' end of the leading strand and at 5' end of each okazaki fragment of lagging strand |
DNA pol III | Using parental DNA as a template, synthesizes new DNA strand by adding nucleotides to an RNA primer or a pre-existing DNA strand |
DNA pol I | Removes RNA nucleotides of promer from 5' end and replaces them with DNA nucleotides added to 3' end of sdjacent fragment |
DNA ligase | Joins Okazaki fragments of lagging strand; on leading strand joins 3' end of DNA that replaces primer to rest of leading strand DNA |
Telomeres | The special nucleotide sequences at the end of Eukaryotic chromosomal DNA |
Chromatin | DNA combined with proteins in a complex |
Nucleosome | The basic unit of DNA packing |