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Cherubism

TermDefinition
Describe the clinical features of Cherubism. This condition is a bilateral expansile radiolucency that widens the alveolus and cause the face to appear large which cause the appearance of the “eyes toward heaven,” with sclera. The enlargement is usually asymptomatic and will increase until puberty.
Describe the demographics of patients diagnosed with Cherubism. There is no gender predilection with diagnosis anywhere between the ages of 1-20 years old. The most common location for the lesions is the posterior jaws. The same lesions may be present in the ribs and humerus. This is a rare condition.
Elaborate on appropriate lesion terminology used to describe Cherubism. The condition is an inherited developmental anomaly and can be described as a bilateral fibro-osseous lesion.
Describe the lesion appearance/histological features of Cherubism: The features are similar to CGCG. The specimen will consist of loose, immature fibrous stroma with scattered multinucleated giant cells. A feature consistent is an eosinophilic cuffing around small vessels. There may be sparse, immature bone present.
List 3 differential diagnosis for Fissured Tongue condition. 1. CGCG 2. Glandular Odontogenic cysts 3. OKC of Nevoid Basal Call Carcinoma
Describe the type of treatment appropriate for Fissured Tongue. The lesion begins to grow prior to 5 years of age and enlarge until puberty then stop growing. Once a biopsy establishes the diagnosis no treatment is required unless pathologic fracture or some other growth-related side effect.
Created by: lesley.carrillo