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BSC1010-Inheritance

PBSC-BSC-The Chromosomal Basis of Inheritance

QuestionAnswer
Name a type of 2n-1 condition: Turner Syndrome
Y-linked genes are found on the _______. Y Chromosome
What is the genotype for a carrier of Galactosemia? Aa*
The male sex chromosomes are _____. XY
Cross a heterozygote and a homozygous recessive individual for Achondroplasia and indicate the percentage of offspring that will get the disease. 50% Achondroplasia
Transfer of a chromosome segment to a non-homologous chromosome is: Translocation
What genotype does not have the disease for the autosomal dominant disorders? Homozygous Recessive
Name a 2n+1 condition which is due to an XXY condition. Klinefelters
Cross a homozygous dominant individual with a homozygous recessive individual for Huntington's and determine the percentage of offspring who will have the disease. 100%
What is another name for Down's Syndrome? Trisomy 21
Huntington's Disease is which type of heritable disorder? Autosomal Dominant
What are the two possible genotypes for males in hemophilia? Xy, X*y
Those chromosomes which are not sex chromosomes. autosomes
Name a type of disease that is in the category of x-linked recessive. Hemophilia
Name a type of genetic disorder that is in the autosomal recessive cate.gory. Galactosemia
Name one disease other than Huntington's that is autosomal dominant: Achondroplasia
Loss of a chromosomal segment by viral attack, replication errors, chemical action or irradation is known as ______. Deletions
Is Down Syndrome a 2n+1 or 2n-1 condition? 2n+1 Condition
Extra DNA inserted into a chromosome is a_______. Duplication
Cross a female Hemophiliac with a normal male. What percentage of the MALES will have Hemophilia? 100%-all
Cross a carrier with a homozygous recessive individual for Galactosemia and indicate the percentage of offspring with the disease. 50% Galactosemic
Cross a carrier for Hemophilia with a normal male. What percentage of the MALES will have Hemophilia? 50%
Cross a normal female with a Hemophiliac male. What percentage of ALL the offspring are Hemophiliacs? What percentage of just the FEMALES are carriers? 0%; 100%
Cross a carrier for Hemophilia with a normal male. What percentage of the FEMALES will have hemophilia? None
True or False? There is no carrier for an autosomal dominant disorder. True
Cross a carrier with a homozygous dominant individual for Galactosemia and determine the percentage of offspring that would have the disease. None
A visual display of chromosomes arranged from largest to smallest. Karyotype
The female sex chromosomes are _____. XX
Cross a female Hemophiliac with a normal male. What percentage of ALL the offspring will have Hemophilia? 50%
The total number of chromosomes in a 2n - 1 condition is: 45
Another name for 2n-1 conditions in general is: Monosomy
The total number of chromosomes in a 2n+1 condition is: 47
When the gene sequence is reversed. Inversion
Does the heterozygote for Huntington's have the disease symptoms? Has Huntington's
True or False? Genes that are located close to one another on the same chromosome tend to be passed to the same gamete together. True
Another name for 2n + 1 conditions in general is: Trisomy
What is the genotype for a carrier of hemophilia? Xx*
Name all 3 genotypes for females in regards to Hemophilia. XX, Xx*, x*x*
Heritable gene therapies are also known as _______ therapies. Transgenic
X-linked genes are found on the _______. X chromosome