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Enzyme Inhibitors
Question | Answer |
---|---|
What is a competitive inhibitor? | Binds to the active site of an enzyme, preventing formation of ES complexes. |
What are non-competitive inhibitors? | Binds to the allosteric site and changes shape of the active site so it is no longer complimentary to the substrate, and ES complexes can no longer form. |
What is end-product inhibition? | After an enzyme-catalyzed reaction has reached completion, product molecules stay tightly bound to the enzyme so that no more product can be made. |
How does Cyanide act as an inhibitor? | CN- ions bind irreversibly to the enzyme found in mitochondria, inhibiting final stage of aerobic respiration. |
How does Aspirin act as an inhibitor? | Salycyclic acid binds to the enzyme that produces cell-signalling prostaglandins, reducing pain. |