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OMFP 2 Flash Card 1 - Adenomatoid odontogenic tumor(AOT)

Clinical Features of AOT This is an asymptomatic benign neoplasm lesion around the crown of an impacted tooth and is unilocular with some radiopacity within the lucency. There will be a thin sclerotic rim and well-demarcated periphery and can grow and expand the cortex.
Demographics of AOT AOT is much more common in females than in males. It is more common in the age range of 10-19 years old and found on the anterior maxilla. It comprises 5% of all odontogenic tumors.
Lesion appearance microscopically of AOT Spindle-shaped epithelial cells that form sheets and strands surrounded by thin fibrous capsule. The are predominant cystic component instead of solid tumor. They are within tissue in whorled masses of rosette structures called zellballen.
Lesion appearance microscopically of AOT continued The resemble ductal structures and can be mistaken for glandular epithelium. There can be peripheral palisading appearances in the duct. The background has fibrous stroma and epithelial areas and various calcifications can also be observed.
Differential Diagnosis of AOT Possible differentials include calcifying odontogenic cyst, ameloblastic fibro-odontoma, and odontoma
Treatment options for AOT The treatment options for AOT are to surgically curettage and enucleation.
Clinical features of AOT continued This is tooth associated with tumor and can not erupt and is impacted. It is usually 1-2cm and opacity may not always be obvious. Opacity may appear as a snowflake and continue to calcify with globular radiopacity in the tumor.
Clinical features of AOT continued AOT is often in anterior regions and sometimes in posterior regions. It is present in bone and not adjacent tooth and peripheral (extraosseous) forms of the tumor are rare.
Clinical features of AOT continued When it is on the gingiva it appears as small, sessile masses on facial gingiva of maxilla.
Lesion appearance microscopically of AOT continued They appear in globular islands of epithelium and calcifications to dystrophic calcifications. Some are dense enough to see on an X-ray.
Lesion appearance microscopically of AOT continued They can have amorphous areas of calcifications that appear like amyloid but they are not associated with systemic amyloids.
Created by: chelseadirector