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Complement Sys

The Complement system

QuestionAnswer
The complement activation occurs by what three pathways? Classical, Lectin, and Alternative.
The classical pathway is initiated by what? Antibodies of the IgM or IgG classes binding to a multivalent antigen.
The lectin pathway is initiated by what? Binding of lectins such as mannose-binding lectin or members of the ficolin family to microbial surface carbohydrates.
The alternative pathway is initiated by what? When the third component of complement, C3, undergoes nonspecific breakdown. C3b is formed and adheres to a cell surface.
Which complement component function is best describe as to opsonize? C3b
Created by: Microbin