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Complement Sys
The Complement system
Question | Answer |
---|---|
The complement activation occurs by what three pathways? | Classical, Lectin, and Alternative. |
The classical pathway is initiated by what? | Antibodies of the IgM or IgG classes binding to a multivalent antigen. |
The lectin pathway is initiated by what? | Binding of lectins such as mannose-binding lectin or members of the ficolin family to microbial surface carbohydrates. |
The alternative pathway is initiated by what? | When the third component of complement, C3, undergoes nonspecific breakdown. C3b is formed and adheres to a cell surface. |
Which complement component function is best describe as to opsonize? | C3b |