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RNA Virus(sect.3.3)
Picornaviruses-Poliovirus
| Question | Answer |
|---|---|
| Poliomyelitis | Is an acute eteroviral infection of the spinal cord that can cause neuromuscular paralysis. |
| Polio structure | Small nonenveloped icosahedral ssRNA virus. |
| Polio Transmission | Humans only known host. Ingestion of contaminated water. Replication in throat and small intestine>>>viremia>>>CNS paralysis. Death from respiratory failure. |
| Poliovirus eradication target | Who targeted 2005 for polio eradication |
| Poliovirus is resistent to? | acid in stomach. |
| Poliovirus can survive for weeks in what? | water and sewage. |
| Poliovirus has a high prevalence in ? | areas with poor sanitation. |
| Since 1988 the global eradication initiative of the poliovirus has | reduced poliovirus transmission from 125 countries and 350K cases to just 6 countries |
| Which countries have reduced the poliovirus reservoirs | Afghanistan, Egypt and Niger |
| Which 3 countries account for 95% of poliovirus cases? | Nigeria, India and Pakistan. |
| Which country is the greatest risk to the global eradication initiative of the poliovirus? | Nigeria |
| In 2004 the world polio cases rose by ? | 1/3 |
| There were only 784 poliovirus cases in? | 2003 |
| How many cases were there in the year 2004 and Why? | 1185, the vaccine boycott in Nigeria spawned a resurgence of disease. |
| Why did a hardline Islamic Cleric lead the poliovirus immunization boycott? | The Islamic leader claims that the vaccine was part of a U.S. led plot to render Nigeria's Muslims infertile or infect them with AIDS. |
| The poliovirus vaccine boycott triggered? | An outbreak that spread to Benin, chad, Cameroon, Botswana, Central African Republic, and more. |
| How many polio cases were there as of October 18 2005 | 1,392 including endemic areas in Nigeria with 520 cases, India with 39 cases and Yemen having 264 cases and Indonesia with 264 due to importation. |