click below
click below
Normal Size Small Size show me how
DNA Virus(sect.2.3)
Herpesviridae Family-Cytomegalovirus (CMV)
| Question | Answer |
|---|---|
| Cytomegalovirus (CMV) | Herpesviridae family, dsDNA, icosahedral enveloped virus, Largest of the herpes virus, *Produces enlargement of cells and nuclear inclusion bodies in a wide range of tissues, *80% of US pop. infected, *Oral/resp. trans. *Normally subclinical infection. |
| Cytomegalovirus (CMV) related illnes | Is rare and occurs in only 2 groups; Immunocompromised, and Fetal Infections |
| CMV in Immunocompromised | Latent virus is reactivated, inadequet cell-mediated immune response allows frequent severe infections of a variety of organs, retinitis, pneumonia, encephalitis, hepatitis, etc. |
| CMV in Fetal Infections | Primary infection of mother occurs>>>Congenital abnormalities-CMV-major infections cause of mental retardation and other congenital defects. |