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DNA Virus(sect 2.1)

Herpesviridae Family-Herpes Simplex virus (HSV-1 & 2)

QuestionAnswer
Herpes Simplex 1 (HSV-1) Herpesviridae family, ds DNA, icosahedral, enveloped virus.*Cold sores/fever blisters & genital HSV.*40-50% us pop. infected.*Lesions near mouth.*virus remains latent in trigeminal nerve ganglia.*Can cause genital HSV.*Recurrent HSV affect 20% adult pop.
Herpes Simplex 2 (HSV-2) Herpesviridae family, dsDNA, icosahedral, enveloped virus.*Genital HSV family.*Lesions appear within 1 week.*Up to 500K people infected each yr.*Nationwide; 45M or 1 out of 5 of total adolescent & adult pop. infected with HSV-2,
HSV-2 (cont) Subclinical in 75% of patients. *As many as 90% are unaware of infection. *recurrences.*tramission may occur without visible lesions, *neonatal herpes can be very serious.
HSV treatment NO CURE---treatment reduce recurrences: Acyclovir (Zovirax), Valacyclovir (Valtrex), Famciclovir (Famvir).
Herpesviridae Family ds DNA, enveloped icosahedral virus, chronic latent infection for life, reccurrences, 8 human Herpesviruses; (discuss six) HSV-1, HSV-2, VZV, CMV, EBV, HHV-8 (Kaposis Sarcoma virus in AIDS patients.
Created by: mdnlght
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