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Antibiotic Facts
Important Facts about Antibiotics
Question | Answer |
---|---|
What are the 4 possible effects of the simultaneously acting antimicrobial agents on a homogenous microbial population? | Synergism, Addition, Indifference, Antagonism |
Which antibiotic classes need to be frozen to maintain their potency? | Penicillins and Cephalosporins |
What are the 5 resistance methods used by bacteria? | 1)Produce enzymes to destroy the antimicrobial, 2) Cell wall become impermeable to the antimicrobial, 3) Mutated target site no longer binds the antibiotic, 4) Efflux pump, 5) Use an alternate metabolic pathway. |
Sulfonamides are a competitive antagonist to ______ and produce a non-functional analogue of ________? | PABA; folic acid |
What are the 6 types of antibiotic interference? | Folate synthesis, cell wall synthesis, cell membrane function, protein synthesis, DNA replication & repair, and RNA synthesis |
Which antibiotic can cause the permanent discoloration of teeth and bones if taken by pregnant women or children under 8 years of age? | Tetracycline |
Which antibiotic can interfere with bone marrow function? | Chloramphenicol |
Which antibiotic can interfere with developing bones or tendon rupture? | Fluroquinolones (Levofloxacin, Ciprofloxacin, Gatifloxacin, Gemifloxacin) |