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Nucleic Acid set 5
Nucleic Acid Module set 5
| Question | Answer |
|---|---|
| stable, heritable change in nucleotide sequence and may or may not have an effect on the phenotype of an organism | mutation |
| mutations can be classified in terms of their effect on | phenotype |
| change colonial or cellular morphology | morphological mutations |
| kill the organism | lethal mutations |
| expressed only under certain conditions (e.g., high temperature) | conditional mutations |
| changes in metabolic capabilities | biochemical mutations |
| have mutations in biosynthetic pathways,cannot synthesize product of pathway,require product of pathway as nutrient in minimal growth media | auxotrophs |
| grow in minimal media without supplements | prototrophs |
| resistance to pathogen, chemical, or antibiotic | resistance mutations |
| most prevalent form of gene | wild type |
| wild type -> mutant form | forward mutations |
| mutant phenotype -> wild type phenotype | reverse mutations |
| Permanent change in the primary sequence of nucleic acids | genetic mutations |
| What are the two types of genetic mutation? | spontaneous and induced |
| Due to natural phenomena | spontaneous mutation |
| cosmic radiation,DNA pol mistakes,Happens ~ 1 in every 106-1010 divisions,1 mutation in every billion bacteria | spontaneous mutation |
| Produced by chemical or physical agents called mutagens | induced mutation |
| Physical mutagen | UV light |
| Base analogues, Alkylators, Nitrous acid | chemical mutagen |
| What are the two types of mutation? | Substitution and Frameshift |
Created by:
kprout
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