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Virus Module Set 9

cancer-causing virus mechanism: carry oncogene into cell and insert it into host genome
cancer-causing virus mechanism: altered cell regulation due to changes in kinase activity or production of regulatory proteins
cancer-causing virus mechanism: insertion of promoter or enhancer next to cellular oncogene
viroids: infectious agents composed only of circular ssRNA
prions: infectious agent thought to be composed only of protein
viroids DO NOT... act as mRNA molecules
viroids can... cause disease in plants
plant disease-inducing viroids... mechanism unknown and some cause latent infections
viroids RNA may... be replicated by rolling-circle method using host RNA polymerase
prions: cause degenerative diseases in animals
animal degenerative diseases: scrapie, bovine spongiform encephalopathy, Creutzfeldt-Jakob disease
in prions, it's currently thought that... PrP (prion protein) is present in “normal” form in host animal
for animals, exposure to... altered PrP thought to cause disease
Created by: Whereis_raye