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Genetics review
Term | Definition |
---|---|
Gel electrophoresis | A method to separate genetic material (DNA) into different sizes of fragments in order to diagnose genetic fingerprinting. |
Karyotype | A test used to identify the size, shape, and number of chromosomes in a cell. It allows to identify chromosomal mutations and the gender of an organism. |
Crossing over | A process in which genes are exchanged between homologous chromosomes to create genetically diverse gametes. This process occurs during prophase 1 of meiosis. |
Genetic Variation | Accomplished by crossing over in meiosis. |
Gametes | Haploid cells commonly known as sex cells (Eggs or Sperm). |
Homozygous dominant | A genotype with two dominant alleles. Represented by two capital letters- BB |
Heterozygous | A genotype with one dominant allele and one recessive allele. Represented by a capital letter and lower case letter- Bb |
Homozygous recessive | A genotype with two recessive alleles. Represented by two lower case letters-bb. |
Nondisjunction | A chromosomal mutation where a chromosome or chromatids fail to separate correctly during cell division- meiosis or mitosis. This results in daughter cells with extra chromosomes or with fewer chromosomes. |
Cancer | Uncontrolled cell division due to faulty checkpoints in the cell cycle. These cells typically skip G-0 and continue dividing constantly. |
Deletion mutation | A gene mutation in which one base or several bases are deleted from the gene leading to a frameshift of the reading frame. |
Substitution mutation | A gene mutation where one base is substituted for another base. |
Dominat Allele | The variant gene that is always expressed. |
Recessive Allele | The variant gene that is only expressed when its part of a homozygous genotype. |
Cell cycle | The life of a cell that includes the stages of G1, S, G2 and M. |
Meiosis | A type of reduction division that results in four genetically diverse gametes (sex cells). |
Mitosis | A type of division that results in two identical somatic (body) cells. |