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biochem enzymes nbde
| Question | Answer |
|---|---|
| hexokinase | 1st phosphorylation of glycolysis |
| glucose 6 phosphatase | opposite of hexokinase reaction but in gluconeogenesis. Def = Von Gierke's |
| G-6-P dehydrogenase | takes G6P into HMP shunt |
| transketolase | brings back R5P to glycolytic pathway from HMP shunt as F6P |
| PFK | Rate limiting of glycolysis, adds 2nd phosphate to glucose to make F1,6,BP |
| Aldolase | breaks F16BP to 2-3 carbon molecules, glyceraldehyde and HDAP. |
| Pyruvate kinase | Removes the last phosphate from PEP to make pyruvate |
| pyruvate dehydrogenase | makes acetyl-coa from pyruvate to go into TCA |
| pyruvate carboxylase | makes oxaloacetate directly from pyruvate, part of gluconeogenesis |
| PEP carboxykinase | takes oxaloacetate back up skipping pyruvate and going directly to PEP for gluconeogenesis |
| citrate synthase | 1st step in tca. makes citrate from acetyl coa and oxaloacetate |
| ornithine transcarbamylase | 1st part of urea cycle. ornithine + carbamoyl phosphate = citrullline. |
| HMG coa reductase | rate limiting of cholesterol synth |
| alpha ketoglutarate dehydrogenase | makes succinyl coa from alpha keto glut |