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Lymphoid Organs/Traf
Question | Answer |
---|---|
What are the primary lymphoid organs? | Bone marrow and Thymus Gland |
What happens in the primary lymphoid organs? | lymphocyte maturation and development |
What are the primary lymphoid organs? | Lymph nodes, Peyers patches, Spleen |
What do lymphoid organs all have in common? | Lymphoid follicles |
What do lymphoid organs al have in common (apart from the spleen)? | High endothelial venules |
Do fDC come from haemotopoesis? | No |
What cells do fDC activate? | B cells |
How do fDC pick up opsonised antigens? | CR and Fc receptor |
What survival signals do newly activated B cells need? | CD40L -CD40 from the Th cells |
What does the spleen sample? | The blood |
What do peyers patches sample? | The intestinal tract |
What surface molecule expression do immature T cells have when arriving in the thymus? | None |
When T cells become double positive, what do they express? | CD4 and CD8 |
What are CTECs? | Cortical thymic epithelium cells |
In the cortex, cells that recognise self peptides/antigens, their fate is that they ___ | Survive |
In the medulla, the T cells are single positive. What does this mean? | they only express either CD4 or CD8 |
What interaction is needed to enter the lymph node? | L-Selectin = GlyCAM-I |
What interaction is needed to enter the peyers patches? | Integrin alpha4beta7 = MADCAM-I |