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Enzymes - 01
Inhibitors and Inducers
| Question | Answer |
|---|---|
| CBZ | Inducers |
| Phenytonin | Inducers |
| Phenobarbital | Inducers |
| Primidone | Inducers |
| Rifampin | Inducers. Also low effectiveness of OC (avoid inducers) |
| Smoking | Inducers |
| St. John's Wort | Inducers |
| Ketoconazole | Inhibitor. pH dependence absorption |
| Itraconazole | Inhibitor. pH dependence absorption |
| Cimetidine | Inhibitor |
| Clarithromycin | Inhibitor |
| Erythromycin | Inhibitor |
| Amiodarone | Inhibitor |
| Paroxetine | Inhibitor |
| Fluoxetine | Inhibitor |
| Fluoxetine | Inhibitor |
| Fluvoxamine | Inhibitor |
| Grapefruit juice | Inhibitor |
| Ritonavir | Inhibitor |
| Indinavir | Inhibitor |
| Decrease INR | Rifamin (other Inducers), eat more foods, nutritional drinks |
| Digoxin special | Increase level with Ery and Clari (ACE), decreased renal unction and low K |
| Special of Ganciclovir (Cytovene) and Zidovudine (Retrovir) | increase risk of anemia and neutropenia |