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Micro Unit Three

Pre-Vaccine. Gives a small dose of disease to help person build immunity. Variolation
Weakened Pathogen. Uses whole, live microbe. >95% effective. (I.e. Measles, Mumps, and Rubella Vaccine) Attenuated Whole Agent
Uses killed microbe (I.e. Influenza) Inactivated Whole Agent Vaccine
Inactivated toxins (I.e. Tetanus) Toxoids
Use only antigenic fragment of a microorganism that best stimulates an immune response. Produced by modifying other microbes to produce the desired fragments (I.e. Hepatitis B) Sub-unit Vaccine
Used to deal with children with a poor/weak immune response (I.e. Very young infants) Conjugate Vaccine
New experimental vaccines. Can be given without needles. Given with gene gun. Nucleus Acid/DNA Vaccines
Probability that a diagnostic test is reactive if specimen is a true positive. Sensitivity
Probability that a positive diagnostic test will not be reactive if specimen is a true negative. Specificity
Antigen reacts with antibodies to create lattice structure forming a precipitate Precipitation Rxn
A test performed on an agar plate requiring the correct concentration of antigens an antibodies Immunodiffusion Test
Precipitation test used for large cellular antigens like RBCs Direct Agglutination Test
Precipitation test used for small and soluble antigens. Indirect Agglutination Test
Precipitation test used for blood typing Hemagglutination Test
Precipitation test that combines fluorescent dyes with serum then exposes it to UV light. Fluorescent Antibody Technique
Direct and Indirect test for blood in urine Enzyme Linked Immunosorbent Assay (ELISA) D
A hypersensitivity rxn seen 2-30 minutes after exposure to antigen. Characterized by IgE antibodies binding to basophil+mast cells. Type I Anaphylactic
A hypersensitivity rxn seen approximately 5-12 hours after exposure to antigen characterized by IgG and IgM antibodies binding to target cells to activate the complement system Type II Cytotoxic
A hypersensitivity rxn seen approximately 3-8 hours after exposure to antigen characterized by antibody+antigen complex which can cause damaging inflammation Type III Immune Complex
A hypersensitivity rxn seen approximately 24-48 hours after exposure to antigen characterized by the utilization of Cytotoxic T-cells Type IV Delayed Cell-mediated
A potential pregnancy complication caused by the mother having a negative blood type and the father having a positive blood type Hemolytic Disease of the Newborn
Define: Hybridoma (A.K.A. Monoclonal Antibodies) Cancer cell+ B-cell that is used in diagnostic test
Define: Antibiotic A substance produced by microorganisms that, in small amounts, inhibit another microorganism.
Define: Bactericidal An anti-microbial agent that works by killing bacteria directly
Define: Bacteriostatic An anti-microbial agent that inhibits growth of bacteria, which allows the body's immune system to kill the pathogen
Created by: Jeremythompson