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Micro Unit Three
| Question | Answer |
|---|---|
| Pre-Vaccine. Gives a small dose of disease to help person build immunity. | Variolation |
| Weakened Pathogen. Uses whole, live microbe. >95% effective. (I.e. Measles, Mumps, and Rubella Vaccine) | Attenuated Whole Agent |
| Uses killed microbe (I.e. Influenza) | Inactivated Whole Agent Vaccine |
| Inactivated toxins (I.e. Tetanus) | Toxoids |
| Use only antigenic fragment of a microorganism that best stimulates an immune response. Produced by modifying other microbes to produce the desired fragments (I.e. Hepatitis B) | Sub-unit Vaccine |
| Used to deal with children with a poor/weak immune response (I.e. Very young infants) | Conjugate Vaccine |
| New experimental vaccines. Can be given without needles. Given with gene gun. | Nucleus Acid/DNA Vaccines |
| Probability that a diagnostic test is reactive if specimen is a true positive. | Sensitivity |
| Probability that a positive diagnostic test will not be reactive if specimen is a true negative. | Specificity |
| Antigen reacts with antibodies to create lattice structure forming a precipitate | Precipitation Rxn |
| A test performed on an agar plate requiring the correct concentration of antigens an antibodies | Immunodiffusion Test |
| Precipitation test used for large cellular antigens like RBCs | Direct Agglutination Test |
| Precipitation test used for small and soluble antigens. | Indirect Agglutination Test |
| Precipitation test used for blood typing | Hemagglutination Test |
| Precipitation test that combines fluorescent dyes with serum then exposes it to UV light. | Fluorescent Antibody Technique |
| Direct and Indirect test for blood in urine | Enzyme Linked Immunosorbent Assay (ELISA) D |
| A hypersensitivity rxn seen 2-30 minutes after exposure to antigen. Characterized by IgE antibodies binding to basophil+mast cells. | Type I Anaphylactic |
| A hypersensitivity rxn seen approximately 5-12 hours after exposure to antigen characterized by IgG and IgM antibodies binding to target cells to activate the complement system | Type II Cytotoxic |
| A hypersensitivity rxn seen approximately 3-8 hours after exposure to antigen characterized by antibody+antigen complex which can cause damaging inflammation | Type III Immune Complex |
| A hypersensitivity rxn seen approximately 24-48 hours after exposure to antigen characterized by the utilization of Cytotoxic T-cells | Type IV Delayed Cell-mediated |
| A potential pregnancy complication caused by the mother having a negative blood type and the father having a positive blood type | Hemolytic Disease of the Newborn |
| Define: Hybridoma (A.K.A. Monoclonal Antibodies) | Cancer cell+ B-cell that is used in diagnostic test |
| Define: Antibiotic | A substance produced by microorganisms that, in small amounts, inhibit another microorganism. |
| Define: Bactericidal | An anti-microbial agent that works by killing bacteria directly |
| Define: Bacteriostatic | An anti-microbial agent that inhibits growth of bacteria, which allows the body's immune system to kill the pathogen |