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Chemo-drugs

Capstones

QuestionAnswer
Methotrexate Antimetabolite - Muocsitis
Pemetrexed Antimetabolite -Mucositis
5-FU Antimetabolite - Mucositis
Capecitabine (Pro-drug of 5-FU) Antimetabolite - Mucositis
Cytarabine Antimetabolite - Mucositis
Gemcitabine Antimetabolite - Mucositis
6-MP Antimetabolite - Rash
Fludarabine Antimetabolite - Infection
Vinca Alkaloids ADR Neuropathies
Vincristine Vinka alkaloids - Neuropathies
Vinblastine Vinka alkaloids - Neuropathies
Vinorelbine Vinka alkaloids - Neuropathies
Paclitaxel Texans - Neuropathies, Infusion reaction
Docetaxel Texans - Neuropathies
Abrazane New Taxel = No problems with reactions. for Refractory to paclitaxel
Topotecan Topo I - MLP (severe)
Irinotecan Topo I - Severe Diarrhea (must treat aggressive)
Etoposide Topo II - MLP, Hypotension. Max dose 0.4mg/mL
Teniposide Topo II - MLP
Doxurubicin Anhracyclines - Extravasation, Discolored secretion, Cardiotoxicity
Idarubicin Anhracyclines - Extravasation, Discolored secretion, Cardiotoxicity
Epirubicin Anhracyclines - Extravasation, Discolored secretion, Cardiotoxicity
Especial about Anthracyclines (-rubicin) Has max life dose of 450-550 mg/m2
Cyclophosphamide Alkylating Agents - N/V, MLP, Secondary malignancies
Dacarbazine Alkylating Agents - N/V, MLP, Secondary malignancies
Melphalan Alkylating Agents - N/V, MLP, Secondary malignancies
Temozolamide Alkylating Agents - N/V, MLP, Secondary malignancies
Cisplatin Heavy metals - Nephrotoxicity, Delay N/V
Carboplatin Heavy metals - Nephrotoxicity, Delay N/V
Oxaliplatin Heavy metals - Nephrotoxicity, Delay N/V
Created by: _Tom_
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