Busy. Please wait.
Log in with Clever

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever

Username is available taken
show password

Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't Know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

BIO Chapter 16

Molecular Basis of Inheritance

Chargaff- investigated DNA composition in different species, determined DNA held genetic material
DNA replication- the process of how DNA is copied
Structure of DNA is- double stranded, helix
Sugar and phosphate groups form ___________of DNA- backbone
What makes up DNA? sugar, phosphate group, nitrogenous base
What two things pair to make the rungs of the ladder of DNA? purine and pyrimidine
Replication/origin sites- spots along the length of eukaryotic DNA where replication starts
Semi-conservative replication- proposed by Watson and Crick, the idea that DNA has to replicate itself
Initiator protein- binds to the origin sight before replication can begin
Helicases- unwinds at the site of origin
SSB proteins- bind to single strands to hold DNA in unwound position
Topoisomerase enzymes- relieve the supercoiling upstream of DNA replication by clipping the rejoining DNA strands
Primase- enzyme made of RNA that synthesizes a short sequence of nucleotides called a primer that compliments the DNA template. New DNA strand grows from this.
DNA polymerases- catalyze the synthesis of DNA, takes appropriate nucleoside triphosphate and attaches it to the 3’ OH terminal of new DNA
What direction do enzymes add nucleotides in? – 5’ Right Arrow 3’
Nucleotide- phosphate group, sugar, nitrogenous base that, put together, make up DNA
Replication fork- a y-shaped portion where parent DNA is being unwound
Single strand binding proteins- bind to unpaired DNA strands to keep them from re-pairing
Primer- RNA chain synthesized by primase
Leading strand- The strand created by the polymerase on the top of a bubble
Lagging strand- bottom strand of a bubble that has to be replicated away from the replication fork
DNA Ligase- joins sugar-phosphate backbones of all Okazaki fragments
Okazaki fragments- fragments of the lagging strand
Proof-reading and repairing DNA- Checks the new nucleotides and replaces the incorrectly pairing nucleotides
Mismatch repair- many repair enzymes remove and repair DNA mismatches after synthesis occurs
Nucleotide excision repair- repairs larger-scale damage to DNA strand
Telomeres- the ends of chromosomes, short nucleotide sequences repeated countless times, protect organic genes
Repeated sequence in humans- TTAGGG
Packaging of chromatin involves- DNA, Histones, Nucleosomes, 30 nm fiber, looped domains, metaphase chromosome
Histones- protein responsible for the first level of DNA packing in chromatin
Nucleosomes- histones coiled with DNA strands
30 nm Fiber- interactions between the histone tails and linker DNA, pulls it all in tighter
Loops domains- 30 nm fiber forms loops, making a tighter fiber
Chromosomes- packed histones and DNA
Chromatid- one half of a chromosome
Created by: mr_spangler
Popular Biology sets




Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
restart all cards