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NAPLEX - 30 MIN

Specific Side Effects

QuestionAnswer
Cyclosprine (Sandiummune) Liver and nephrotoxicity
Tacrolimus (Prograf) Hyperlakemia and Nephrotoxicity
Sirolimus (Rapamune) Hypotension, nephrotoxicity, Elevated serum Cholesterol Level
Sumatriptan (Imiterx) Seizure, corneal opacity
Cisplatin (Platinol) Renal toxicity, Ototoxicity, Servere N/V
Indomethacin (Indocin) Renal and Liver toxicity, GI bleeding
Ketorolac (Toradol) GI bleeding, Perforatin of stomach, peptic ulcer
Morphine (MSIR) Constipation, Respiratory depression, pinpoint pupil constriction
Tramadol (Ultram) Seizure with Alcohol
Methimazole (Tapazole) Agranulocytosis, Hepatitis
Metformin (Glucophage) Lactic acidosis, Metallic taste, Anorexia
Rosiglitazone (Avandia) or Pioglitazone (Actos) Jaundice and Liver toxicity
Acarbose (Precose) flatulence, Diarrhea and Abdominal cramping
Zidovudine (Retrovir) Severe Anemia and Granuloytopenia
Rifampin (Rifadin) Hepatotoxicity and Hyper-bilirubinemia
Abacavir (Ziagen) Severe Rash
Nevirapine (Viramune) Severe Rash
Efavirenz (Sustiva) Severe Rash
Delavirdine (Rescriptor) Severe Rash
Pyrazinamide (PZA) - combo to treat TB Hepatotoxicity, Hyperuricemia, Interstitial Nephritis
Isotretinoin (Accutane) Cheilitis, Liver failure, Visual disturbance, Hyperglycemia
Aluminum Hydroxide Constipatoin
Magnesium hydroxide or Carbonate Diarrhea
Calcium Carbonate/Sodium Carbonate Milk alkali syndrome
Misoprotols (Cytotec) Severe diarrhea
Sucralfate (Carafate) Constipation
Amphetamine CNS stimulation, blurred vision, seizure and insomnia
Sibutramine (Meridia)- Tx of obesity CNS stimulation and Insominia
Orlistat (Xenial) Fecal urgency, fatty/oily stool
Phenylbutazone (PBZ) - Gout, Arthritis Aplastic anemia
Hydroxychloroquin (Plaquenil) Retinopathy
Methotrexate (Rheumatrex) Liver and Renal toxicity, hematological toxicity, stomatitis
Penicillamine (Depen) SLE, Aplastic anemia, thrombocytopenia
Cyclophosphamide (Cytoxan) - RA hemorrhagic cystitis
Theophylline Tachycardia, seizure and arrhythmia
Etanercept (Embrel) Sepsis, serious infections, seizure, depression
Anakinra (Kineret) -- RA Serious infections and neutropenia
Infliximab (Remicade) Liver toxicity and blood disorders
Ephedrine Insomnia, confusion, nervousness
Sargramostim (Leukine) Peripheral edema --> for increase WBC production
Pegfilgrastim (Neulastia) An enlarged spleen or splenic repture --> CSF
Colchicine Severe diarrhea and blood abnormality
Sulfinpyrazone (Anturan) Blood dyscrasia and bleeding
Tacrine (Cognex) Liver toxicity, seizure and neutropenia
Created by: _Tom_
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