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NAPLEX - CANCER

Chemo Drug Classes

QuestionAnswer
5-Flourouracils (5-FU) Antimetabolites
Capecitabine Antimetabolites
Cytarabine Antimetabolites
Gemcitabine Antimetabolites
6-MP Antimetabolites (Rash)
6-TG Antimetabolites
Fludarabine Antimetabolites (Infection - b/c it's killing lymphoytes)
Cladribine Antimetabolites
Pentostatin Antimetabolites
Methotrexate Antimetabolites (Antifolates)
Vincristine Anti-spindle fiber (Vinca alkaloids) (Neuropathies)
Vinblastine Anti-spindle fiber (Vinca alkaloids) (Neuropathy)
Vinorelbine Anti-spindle fiber (Vinca alkaloids) - Pancreatitis
Paclitaxel Anti-spindle fiber (Taxanes) = Neuropathy
Docedtaxel Anti-spindle fiber (Taxeanes) = Neuropatheis
Topotecan Topoisomerase Inhibitors
Ironotecan Topoisomerase Inhibitors - Diarrhea
Etoposide Topoisomerase Inhibitors - Hypotension, secondary malignancies
Teniposide Topoisomerase Inhibitors
Doxorubicin Anthracyclines - Cardiotoxicity, Discolored secretions (urine, sweat red)
Daunorubicin Anthracyclines - Cardiotoxicity, Discolored secretions (urine, sweat red)
Idarubicin Anthracyclines - Cardiotoxicity, Discolored secretions (urine, sweat red)
Epirubicin Anthracyclines - Cardiotoxicity, Discolored secretions (urine, sweat red)
Mitoxantron Anthracyclines
Dacarbazine Alkylating Agents
Melphalan Alkylating Agents
Cyclophosphamide Alkylating Agents
Temozolamide Alkylating Agents
Cisplatin Heavy metals
Carboplatin Heavy metals
Oxaliplatin Heavy metals
Interferon alfa-2A (Roferon-A) Immune Modulators (flu-like symptoms)
Interleukin-2 (Proleukin) Immune Modulators (flu-like symptoms)
Thalidomide Immune Modulators - VTE, Neuropathy
Lenalidomide Immune Modulators - VTE, Peripheral edema
Bortezomib (Velcade) Intracellular Protein Inhibitors (rash)
Imattinib Intracellular Protein Inhibitors (rash)
Geftinib Intracellular Protein Inhibitors (rash)
Erlotnib Intracellular Protein Inhibitors (rash)
Sunitinib Intracellular Protein Inhibitors (rash)
Monoclonal Abx (Mu, Zu, Zi, Mo) Origin = Human, Humanized, Chimeric, Mouse)
Tamoxifen SERM = ADR: Hot flashes, thromboembolic even, endometrial cancer
Megestrol (Megace) 160mg/d Aromatase Inhibitors - Breast Cancer
Anastrazole (Arimidex) 1mg/d Aromatase Inhibitors - Breast Cancer
Letrozole (Femara) 2.5mg/d Aromatase Inhibitors - Breast Cancer
Exemestane Aromatase Inhibitors - Breast Cancer
Leuprolide LHRH agonist - Protate cancer
Goserelin LHRH agonist - Protate cancer
Bicalutamide Anti-Androgens - Prostate cancer
Flutamide Anti-Androgens - Prostate cancer
Nilutamide Anti-Androgens - Prostate cancer
Created by: _Tom_
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