Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
control. micr. grow
controlling microbial growth
| Term | Definition |
|---|---|
| Principles of controlling microbial growth | 1. Microorganisms have specific requirements 2. Certain structures and/or processes are essential 3. Any control strategy has to be tailored 4. Not all control methods are equally effective 5. Not all microorganisms are equally susceptible |
| UV-rays sterilisation | 1. UV range: 50-400 nm wavelength 2. Absorbed by purine & pyramidine bases: forms pyramidine dimers 3. Doesn’t penetrate well: limited to surface sterilization 4. Uses: Sterilize some foods E.g., nuts and spices. |
| Ionizing | Dislodges electrons from atoms Damages DNA and produces peroxides |
| Disinfectants | 1. Quaternary ammonium compound 2. Halogens (iodine, chlorine) 3. Peroxides 4. Alcohols |
| Function of antibiotics: Chloramphenicol, Streptomycin, Tetracyline, Macrolides. | Protein synthesis inhibition |
| Antibiotics targeting protein synthesis inhibition | Chloramphenicol, Streptomycin, Tetracyline, Macrolides. |
| Selective toxicity | Antibiotics that kill microbial cells but not the host's cells. |
| Has stationary number of total cells and low number of viable cells | bactericidal compound |
| bactericidal compound | Has stationary number of total cells and low number of viable cells |
| Has a low total cell count and a low viable cell count | Bacteriolytic compound |
| Key features of Antiseptics | 1. How effective it is depends on: antimicrobial activity and toxicity to living tissues. 2. ability to remove microbes before injection 3. ability to reduce numbers of microbes before cut or surgery |
| Dilution test | ring dipped in colony --> ring washed with disinfectant --> ring washed with water --> ring put in nutrient broth --> effectiveness of disinfectant based on growth in broth. |
| ring dipped in colony --> ring washed with disinfectant --> ring washed with water --> ring put in nutrient broth --> effectiveness of disinfectant based on growth in broth. | Dilution test |
| Therapeutic antimicrobials | General term that is used to refer to natural and synthetic compounds with activity against microorganisms, that can be used therapeutically. |
| General term that is used to refer to natural and synthetic compounds with activity against microorganisms, that can be used therapeutically. | Therapeutic antimicrobials |
| Inhibitors of Reverse Transcriptase | Zidovudine (AZT) and Stavudine |
| Mechanisms of Zidovudine (AZT) and Stavudine | NUCLEOSIDE ANALOG: Activated (phosphorylated) inside the infected cell and Inhibit the viral polymerase (reverse transcriptase) |
| Inhbitors of petidigylcan syntehsis | Beta lactam antibiotics: Penicillin and Cephalosporins |
| Mechanism of Beta lactam antibiotics: Penicillin and Cephalosporins | Blockage of synthesis of cross linkage in the peptidoglycan layers. Binds to the enzymes (transpeptidases) responsible for the cross-linking. |
| Main targets for antibacterial action | 1. Protein synthesis 2. Metabolism 3. Cell wall 4. Cell membrane function 5. Nucleic acid synthesis |
| Ergosterol | A steroid alcohol present in fungal cell membrane (responsible for stiffening the cell membrane) |
Created by:
1127014594018074
Popular Biology sets