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Pharmacology Drugs

Drugs To Remember Exam 2

QuestionAnswer
Trimethaphan Ganglionic Blocking Drug of ANS; blocks neuronal nicotinic acetylcholine receptors to block transmission at autonomic ganglia
Norepinephrine SNS; Endogenous Agonist; noradrenaline, in adrenal cortex; released from sympathetic neurons, binds to a1, a2, b1, b3 adrenergic receptors (low affinity for b2)
Neuropeptide Y SNS; endogenous agonist; coreleased with NE at many sympathetic nerve terminals
Adenosine triphosphate (ATP) SNS; endogenous agonist; coreleased with NE at many sympathetic nerve terminals
Epinephrine SNS; endogenous agonist; released from adrenal gland, binds to a1, a2, b1, b2 adrenergic receptors; adrenaline, made in adrenal medulla
Phenylephrine SNS; Sympathomimetics; preferentially activates a1 adrenergic receptors
Clonidine SNS; Sympathomimietics; preferentially activates a2 adrenergic receptors
Isoproterenol SNS; Sympathomimetics; activates both b1 and b2 adrenergic receptors
Amphetamine SNS; Indirect acting sympthomimetic; facilitates release of NE from nerve terminal and blocks its reuptake
Prazosin SNS; Sympatholytics; specific a1 adrenergic receptor blocker
Yohimbine SNS; Sympatholytics; specific a2 adrenergic receptor blocker
Propranolol SNS; Sympatholytics; nonspecific b adrenergic receptor blocker
Acetylcholine (ACh) PNS; Endogenous agonist; activates nicotinic acetylcholine receptors present at neuromuscular junction and in autonomic ganglia, as well as mucarinic acetylcholine receptors present at the neuroeffecctor junction for the PNS
Carbamlcholine (Carbachol) Cholinomimetics (imitate ACh); cholinergic agnosit which is somewhat selective for muscarinic subtype of ACh receptors
Neostigmine Cholinomimetics; PNS; cholinesterase inhibitor, use of which prevents the breakdown of ACh, prolonging the duration ACh activity at its receptors
Atropine Muscarinic Blocking Drugs; PNS; prototypic muscarinic ACh receptor blocking agent
Acetylcholine Endogenous agonist for motor nervous system; released from motor neuron and binds to nicotinic ACh receptors present at the neuromuscular junction
d-(+)tubocurarine (Curare) Nondepolarizing blocking agent of Motor Nervous System: classical blocking agent for nicotinic ACh receptors at the neuromuscular junction
Succinylcholine depolarizing neuromuscular blocker for motor nervous system; binds to and activates nicotinic ACh receptors at the neuromuscular junction; broken down more slowly than ACh, leading to prolonged activation (and inactivation) of AChR at the neuromuscular
Created by: austar01
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