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Antimicrobials
Antimicrobials - Keywords
Term | Definition |
---|---|
Empirical treatment | Based upon clinical symptoms, signs, laboratory findings, and epidemiologic informaiton |
Definitive treatment | Based upon results of microbiologic tests and where appropriate, in vitro antimicrobial susceptibility testing |
In vitro susceptibility testing | Measure of an antimicrobial agent required to inhibit or kill organisms in vitro compared with the expected concentration of the drug achieved in the blood or urine with usual dosages of the drug in healthy volunteer subjects or in moderately ill patients |
MIC-50 | edian antibiotic concentration at which one-half of strains are more sensitive |
MIC-90 | Concentration that inhibits 90% of the isolates |