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Viral + Systemic

NRTI’s Zidovudine, Didanosine, Lamivudine, Stavudine, Abacavir
NNRTI’s Nevirapine, Delavirdine, Efavirenz
Picornaviruses Perch on a ‘pic’ Poliovirus, Echovirus, Rhinovirus, Coxackievirus, HAV. No envelope, ss Linear RNA, Icosahedral. Aseptic meningitis (-HAV, Rhino). 1 polypeptide that’s cleaved.
Arboviruses Flavi, Toga, Bunya
DNA Viruses (+non-envelOped) Herpesvirus, Hepadnavirus, AdenOvirus, ParvOvirus, PapillOmavirus, PolyOmavirus, Poxvirus
SS DNA Virus Parvovirus B19 (SickleSell anaplastic crises/ Part ov a virus)
RNA Viruses [Non-Enveloped] [Picornavirus, Hepesvirus, Reovirus] Flavi-, Toga-, Retro-, Corona-, Orthomyxo-, Paramyxo-, Rhabdo-, Filo-, Arena-, Bunya-, Delta-
DS RNA Virus Reovirus (repeatovirus)
Circular RNA Virus Arenavirus, Bunyavirus, Deltavirus
Killed Virus Vaccines Rabies, influenza, Salk Polio & HAV
Recombinant Virus Vaccines HBV
Live Attenuated Vaccines MMR, Sabin Polio, VZV, Yellow Fever, Smallpox
Complementation Co-infx w/ a dysfunctional mutated virus & a normal one from a different species that covers it’s ass
(-) Strand Viruses Always Bring Polymerase Or Fail Replication Horribly (Arena-, Bunya-, Paramyxo-, Orthomyxo-, Filo-, Rhabdo-, Hepatitis d)
Segmented RNA Viruses Bunya-, Orthomyxo-, Arena-, Reo- (Orthomyxo is flu, facilitates antigenic shift -> new flu pandemic)
CD4 <400 Thrush, VZV, TB reactivation, bacterial infx (H flu, pneumococcus, salmonella)
CD4 <200 HSV reactivation, disseminated coccidiomycosis, PCP
CD4 <100 Toxo, histo, Candida esophagitis
CD4 <50 CMV, disseminated MAC, cryptococcal meningitis
HIV neoplasms HPV, PCL, NHL, KS
Neonatal Pneumonia GBS, E coli
Pediatric Pneumonia RSV, Mycoplasma, Chlamydia, Pneumococcus,
20-40 Pneumonia Mycoplasma, Chlamydia, Pneumococcus
40-65 Pneumonia Pneumococus, H Flu, Anaerobes, viruses, mycoplasma
Elderly Pneumonia Pneumococcus, Viruses, Anaerobes, H Flu, G (-) rods
Nosocomial [+ Immunocompromised] Pneumonia Staph, G(-) rods, [+fungi, viruses, PCP]
Neonatal Meningitis GBS, E Coli, Listeria
Pediatric Meningitis (6 mos-6 yrs) Pneumococcus, Meningitidis, H flu, Enteroviruses
6-60 yrs old Meningitis Meningitidis, Enterovirus, Pneumococcus, HSV (->AMS)
Elderly meningitis Pneumococcus, G(-) rods, Listeria
Viral causes of Meningitis Coxackie, HSV, HIV, WNV, VZV
Osteomyelitis When in doubt, S. aureus. Often elevated CRP & ESR
UTIs Ambulatory: E coli (metallic sheen) > Saprophyticus > Klebsiella. Nosocomial: E Coli, Proteus, Klebsiella, Serratia (+/- red pigment), Pseudamonas. Leukocyte Esterase: Bacterial. Nitrite (+): G (-)
ToRCHHeS Infx (Vertical xmission) Toxoplasma, Rubella, CMV, HIV, HSV2, Syphilis
Created by: Kyle Tiemeier