click below
click below
Normal Size Small Size show me how
Reproduction
Question | Answer |
---|---|
HFG Syndrome | Bicornuate uterus/hypospadias, deformed hands, feet. HomeoboxA-13 mutation. |
XXY | Abnormal Leydig & Sertoli->High FSH & LH. Barr Body |
Hydatiform Mole | Empty egg-> Diploid sperm contribution (Complete), tripoid or tetraploid (Partial) w/ greater development. Coriocarcinoma precursor. |
Abruptio placentae | Placental detachment: PAINFUL bleeding: associated w/DIC, smoking, HTN, Cocaine |
Placenta accretia | Placental attachment to myometrium. MASSIVE postpartum bleeding. Assoc w/ C-Sec & Inflammation |
Adenomyositis | Endometriosis within the myometrium |
Polycystic Ovarian Syndrome | Amenorrhea, infertility, obesity, hirsutism. Low FSH (semi-developed follicles), high LH->high Testosterone. Insulin resistance, endometrial cancer. Tx: Wt Loss, OCP/Gonadotropin analog, clomiphene |
Follicular Ovarian Cyst | Unruptured graafian follicle. Associated w elevated Estrogen/endometrial hyperplasia |
Corpus Luteum Cyst | Hemorrhage into persistent corpus luteum. Associated w/ menstrual irregularity |
Theca-Lutein Cyst | Bilateral. Due to gonadotropin stimulation. Associated w/ Choriocarcinomas & moles |
Chocolate Ovarian Cyst | Ovarian endometriosis ->blood containing cyst. Cycle-associated. |
Ovarian germ cell tumors | Yolk sac, Choriocarcinoma, Dysgerminoma, Teratoma (MATURE [only non-malignant one], Struma ovarii, immature) |
Ovarian non-germ cell tumors | CA-125. BRCA1, HNPCC Serous Cystadenomas/Cystadenocarcinomas, Mucinous cystadenomas/cystadenocarcinomas, Brenner Tumor, Fibromas, Granulosa Cell tumor, Krukenberg tumor |
Serous Cystadenoma/Cystadenocarcinoma | 70% of ovarian tumors. Bilateral, fallopian tube-like epithelium. Benign/Malignant. |
Mucinous Cystadenoma/Cystadenocarcinoma | Cysts lined w/ mucous secreting epithelium. Benign/Malignant |
Brenner Tumor | Benign, Bladder-like |
Meig's Syndrome Triad | Ovarian fibromas, ascites, hydrothorax. Pulling sensation in groin |
Granulosa Cell Tumor | Estrogen secreting (Precocious puberty). Endometrial hyperplasia ->->carcinomas. Call-Exner Bodies: Follicles w/ eosinophilic secretions |
Krukenberg tumor | GI metastasis to ovary: Mucin-secreting signet cell adenocarcinoma |
Vaginal Clear cell adenocarcinoma | DES exposure |
Yolk sac (Ovarian & Testicular) | Alpha Fetoprotein. Male:Schiller Duval Bodies of primitive glomeruli |
Choriocarcinoma | Ovarian & Testicular. Beta hCG. Women: increased theaca-lutein cysts. |
Dysgerminoma | hCG |
Ductal Papilloma | Serous +/- blood, unilobular & unilateral. Slight malignancy risk. |
Ductal Carcinoma (In-Situ) | Non-invasive, remains within basement membrane. ->Comedocarcinoma. |
Fibroadenoma | Young ppl. Small circumscribed mobile mass. Enlarge in pregnancy. Non-cancerous |
Phyllodes Tumor | Large, clefted leaf-like. Malignant potential. |
Invasive Ductal Carcinoma | Spiculated firm fibrosis. Most common & worst prognosis |
Invasive Lobular Breast Carcinoma | "Indian Lines" multiple, +/-bilateral |
Comedocarcinoma | Ductal, necrosis. Higher grade DCIS. Diffuse paplapble mass. |
Paget's Disease | Ductal epithelium spread. Red nipple. Large clear cells. |
Inflammatory Breast Carcinoma | Lymphatic involvement. Peau d'orange. |
Breast Cancer Risk Factors | Early menarche. Late 1st pregnancy, late menopaus. Family. BRCA1/2, HNPCC, erb-B2 |
XYY | Antisocial |
XO | +/- Mosaic form. Leydig & Theca cell dysgenesis-> high FSH, LH. Horseshoe kidney, bicuspid Aortic valve. High palate. Preductal coarct. |
Testicular Germ Cell Tumors | Seminoma, Embryonal Carcinoma, Yolk Sac, Choriocarcinoma, Teratoma |
Non-Germ Cell Tumors (Sex cord) | Leydig Cell, Sertoli Cell, Testicular Lymphoma. |
Leydig Cell Tumor | Reinke crystals. Androgens-> Gynecomastia, precocious puberty |
Seminoma | Painless. Watery cytoplasm. Radiosensitive & late metastasis. Good prognosis. |
Embyonal Carcinoma | Painful. Poor prognosis. Glandular/papillary. |
Bowden Disease/Erythroplasia of Queyrat | SINGLE erythematous plaque on shaft or scrotum/glans. Risk of carcinoma. |
Reinke Crystals | Leydig Cell Tumor |
Call-Exner Bodies | Theca Cell Tumor |