Reproduction
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show | Bicornuate uterus/hypospadias, deformed hands, feet. HomeoboxA-13 mutation.
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show | Abnormal Leydig & Sertoli->High FSH & LH. Barr Body
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Hydatiform Mole | show 🗑
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Abruptio placentae | show 🗑
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show | Placental attachment to myometrium. MASSIVE postpartum bleeding. Assoc w/ C-Sec & Inflammation
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show | Endometriosis within the myometrium
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show | Amenorrhea, infertility, obesity, hirsutism. Low FSH (semi-developed follicles), high LH->high Testosterone. Insulin resistance, endometrial cancer. Tx: Wt Loss, OCP/Gonadotropin analog, clomiphene
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Follicular Ovarian Cyst | show 🗑
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show | Hemorrhage into persistent corpus luteum. Associated w/ menstrual irregularity
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Theca-Lutein Cyst | show 🗑
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show | Ovarian endometriosis ->blood containing cyst. Cycle-associated.
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show | Yolk sac, Choriocarcinoma, Dysgerminoma, Teratoma (MATURE [only non-malignant one], Struma ovarii, immature)
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show | CA-125. BRCA1, HNPCC Serous Cystadenomas/Cystadenocarcinomas, Mucinous cystadenomas/cystadenocarcinomas, Brenner Tumor, Fibromas, Granulosa Cell tumor, Krukenberg tumor
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show | 70% of ovarian tumors. Bilateral, fallopian tube-like epithelium. Benign/Malignant.
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Mucinous Cystadenoma/Cystadenocarcinoma | show 🗑
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Brenner Tumor | show 🗑
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show | Ovarian fibromas, ascites, hydrothorax. Pulling sensation in groin
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show | Estrogen secreting (Precocious puberty). Endometrial hyperplasia ->->carcinomas. Call-Exner Bodies: Follicles w/ eosinophilic secretions
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Krukenberg tumor | show 🗑
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show | DES exposure
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Yolk sac (Ovarian & Testicular) | show 🗑
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show | Ovarian & Testicular. Beta hCG. Women: increased theaca-lutein cysts.
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Dysgerminoma | show 🗑
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show | Serous +/- blood, unilobular & unilateral. Slight malignancy risk.
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show | Non-invasive, remains within basement membrane. ->Comedocarcinoma.
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Fibroadenoma | show 🗑
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show | Large, clefted leaf-like. Malignant potential.
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show | Spiculated firm fibrosis. Most common & worst prognosis
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show | "Indian Lines" multiple, +/-bilateral
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Comedocarcinoma | show 🗑
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Paget's Disease | show 🗑
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Inflammatory Breast Carcinoma | show 🗑
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show | Early menarche. Late 1st pregnancy, late menopaus. Family. BRCA1/2, HNPCC, erb-B2
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XYY | show 🗑
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show | +/- Mosaic form. Leydig & Theca cell dysgenesis-> high FSH, LH. Horseshoe kidney, bicuspid Aortic valve. High palate. Preductal coarct.
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show | Seminoma, Embryonal Carcinoma, Yolk Sac, Choriocarcinoma, Teratoma
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show | Leydig Cell, Sertoli Cell, Testicular Lymphoma.
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Leydig Cell Tumor | show 🗑
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Seminoma | show 🗑
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Embyonal Carcinoma | show 🗑
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show | SINGLE erythematous plaque on shaft or scrotum/glans. Risk of carcinoma.
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show | Leydig Cell Tumor
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Call-Exner Bodies | show 🗑
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