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Diagnosing Infection
Phenotypic, genotypic, and immunologic methods
| Term | Definition |
|---|---|
| Phenotypic method | Observation of microbe's microscopic and macroscopic morphology, physiology, and biochemical properties |
| Genotypic method | Analysis of microbe's DNA or RNA |
| Immunologic | Analysis of microbe using antibodies, or of patients' antibodies using pre-packaged antigens |
| Microscopic direct testing examples | Gram stain, acid-fast stain, Fluorescent Ab (antibody) stain, gene probes |
| Macroscopic direct testing examples | Direct antigen; gene probes |
| Tests on isolates (exp.) | Biochemical; serotyping; antimicrobial sensitivity; gene probes; phage typing; animal inoculation |