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Biology 4.6

TermDefinition
sorting signals/traffic signals a short amino acid sequence in a protein that directs the protein to its current location
cotranslational sorting the sorting process in which the synthesis of certain eukaryotic proteins begins in the cytosol and then halts temporarily until the ribosome has become bound to the ER membrane
post translational sorting the uptake of proteins into the nucleus, mitochondria, chloroplasts, or peroxisomes that occurs after the protein is completely made in the cytosol
ER signal sequence a sorting signal in a polypeptide usually located near the amino terminus that is recognized by SRP (signal recognition particle) and directs the polypeptide to the ER membrane
signal recognition particle (SRP) a protein/RNA complexes that recognizes the ER signal sequence of a polypeptide, pauses translation, and directs the ribosome to the ER to complete translation
chaperones a protein that keeps other proteins in an unfolded state during the process of post translational sorting
Created by: cinfante16
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