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Central Dogma

Some good Stuff

TermDefinition
Where and when during the cell cycle does DNA replication occur? In the nucleus during the "S" part of inter-phase.
Exactly what gets replicated during DNA replication? The 46 chromosomes in the nucleus, every single one of them gets copied the entire library.
Adenine bonds with _______ Cytosine bonds with ______ Thymine Guanine
Semi-conservative Replication Occurs the two DNA molecules twist into TWO double helices. Each strand is half old and half new.
Helicase Enzyme that unwinds the helix, and separates the two strands. This action requires ATP.
Gyrase (topoisomerase) prevents tangling of the DNA as it unwinds
RNA Primase A special RNA polymerase that that makes short RNA primers that allow DNA polymerase to work. A primer is required because there must be a free 3' OH group available for the addition of each nucleotide.
DNA Polymerase III Recognizes the RNA primer and Synthesizes DNA in the 5'->3' direction.(DNA synthase always occurs in the 5'->3' direction)
DNA Polymerase I Removes the RNA primers and replaces them with DNA.
DNA Ligase (Glue Enzyme) Makes sure that the newly-synthesized DNA is covalently-linked strand.
Leading Strand The DNA strand that is synthesised continuously during replication.
Lagging Strand The strand of DNA whose direction of synthesis is opposite to the direction of the growing replication fork, and is much more complex.
Okazaki Fragments Short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication. They are complementary to the lagging template strand, together forming short double-stranded DNA sections.
The Central Dogma of Molecular Biology DNA makes RNA, RNA makes proteins, and proteins make traits.
How does DNA control the cell By telling the cell what proteins to make.
The three types of RNA -mRNA -tRNA -rRNA
What does protein synthesis make sure of? It makes sure you can form the same protein the same way every time.
Where does Protein Synthesis occur? The first part occurs in the nucleus, and the second part occurs in the Cytoplasm.
When does Protein Synthesis occur? It occurs on an as needed basis, or only when you need that protein.
What gets replicated during Protein Synthesis? 1 gene on one chromosome (this is where the recipe for that protein is located.
What happens during Transcription? The DNA recipe for a protein get copied down or translated into RNA language.
What occurs during translation? (simplified) The RNA message gets copied down in amino acid language, and the protein gets assembled.
What is the tRNA carrying on its other end? The tRNA is carrying a specific amino acid.
What does a ribosome call for in Translation The tRNA with the correct anticodon to match that codon.
Codon Made up of three nitrogenous bases, every three bases is one. AUG|CCC|GAU|GUU etc.
What is the only start codon. AUG or methionine.
Peptide Bond The bond formed by amino acids.
Single-Strand Binding proteins Bind to the sugar phosphate backbone of the DNA molecule so that it can't bind back together
Created by: Eott55
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