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Science Unit 4
Science Unit 4-7 th grade
Question | Answer |
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DNA | genetic material that store information passed on from the parent, based in the nucleus, *doubled stranded *deoyxribose sugar |
RNA | is to act as a messenger carrying instructions from DNA for controlling the synthesis of proteins, *Role in Protein Synthesis *takes place on the Ribosomes in cystoplasm. *starts in nucleus is the one single stranded, *ribosome suga |
Relationship between Amino Acids and Protiens | The order nucleotides determine the order of amino acids, which then form protiens |
Main function of a gene | controls the production of proteins in the organism's cell |
Codons | a sequence of three nucleotides that together form an unit of genetic code in DNA or RNA molecules *used to IDENTIFY amino Acids in the mRNA |
Anti-codons | a sequence of three codons in the tRNA molecules that correspond to complementary codon in the mRNA *Used to CARRY the amino acids |
Protein Synthesis | Production of protein is called |
where does protein production take place | on the ribosomes in the cytoplasm |
mRNA (messenger) | COPIES the instruction of the DNA in the nucleus and carries these codon to the ribosome part of transcription process |
tRNA (transfer) | CARRIES the Amino acids to the ribosomes. shaped a certain way that one end can attach to a specific amino acid- other side is a triple base (anti-codon) |
rRNA (ribosomal) | molecule in the cell that COMPOSES the ribosomes |
how do the bases differ in DNA and RNA? | DNA- ATCG-Thymine RNA- AUCG- uracil |
Transcription | 1 strand of DNA molecule is used to make a single-strand molecule of RNA The process of transferring the nucleotides from DNA to the codon RNA. ONLY individual genes are transcribed, not all of DNA A-U, T-A, G-C mRNA |
Replication | DNA copies itself before the cell divides 1. 2 DNA strands separate. 2. nucleotides match up to the open strand 3. c-G, T-a 4. 2 identical DNA molecules are formed. 5. each molecule has 1 old strand and 1 new strand |
How many templates are used in replication? | 2 templates |
what does DNA replication produce? | 2 identical DNA molecules following the rules of pairing |
where does DNA replication happen? | Interphase (S phase) |
Semi-Conservative model | Watson and Crick showed the two strands of the parental molecule separate and each function as a template for synthesis of a- new complementary strand |
translation | Assembly of the Amino ACIDS To MAKE PROTEINS Replication and transcription involved translating along information that is coded in the language of nucleotides bases to Amino acids. 3 base= 1 Amino Acid tRNA |
Where does translation take place | proteins are made on the ribosomes in the cytoplasm |
Where does Transcription take place | in the nucleus |
Ribosomes | are made up of ribosomal RNA (rRNA) and proteins |
What dos Translation produce | assembles the amino acids into their proper sequence to form protein |
steps of Protein synthesis | 1 mRNA Transcription (copy of the DNA to mRNA) 2. mrNA attaches to Ribosome in cytoplasm 3. Translation (copy of the codon to anticodon to carrying amino acids, to form protien) |
Start codon | AUG (MET) |
Stop codon | UAA, UAG, UGA |
mutation | Changes made to the DNA |
what percentage of DNA in the person's cell are the same | 99.9% |
What percentage of the DNA in a person's cells are genes? | 5% |
3 possible outcomes of mutation | no effect, minor, great |
no effect (mutation) | Mutation does not change protein. it stays neutral- since some amino acids have more than one code, a mutation may not change the resulting protein. |
Minor (mutation) | a change in the gene can affect apperance, skin color, eye color |
Great(major mutation) | causes genetic disorders- passed down to offspring by germ (gamete) cell. seffects can be good, plant having increase resistance to diseases or bad to have an illness. |
what proof reads DNA | certain enzyemes |
are all mutations harmful | no some can be a benefit to the organism, to make them resistance to a pesticides or other disease only 5% of the human DNA is genes, if it occurs in the noncoding region of DNA, then chances are the mutation will have no effect. |
Mutation in somatic cells | mutation of the body cells |
mutation in the Germ cells | mutation in the sex cells, gametes more harmful. they can be passed on to offsprings. |
Chromosomal mutations | changes the structure of the chromosomes *loss or gain |
what are the 5 main types of chromosomal mutation? | Deletion, inversion, duplication, translocation, non-disjunction |
Deletion (chromosomal mutation) | due to breakage of chromosome, a piece of the chromosome is lost |
Inversion (chromosomal mutation) | Chromosome segment breaks off, segment flips around backwards, segment reattaches |
Duplication(chromosomal mutation) | occurs when a gen sequence is repeated |
Translocation (chromosomal mutation) | involves 2 chromosomes that are not homologous, part of the one chromosomes is transferred to another chromosomes |
non-disjunction (chromosomal mutation) | failure of the chromosome to separate during meiosis. causes the gamete to have too many or too few chromosomes |
Gene mutation | *change in the nucleotides sequence of genes * may only involve a single nucleotide, *may be due to copying errors, chemicals or virus |
prime time for mutations to occure | meiosis |
5 main types of gene mutation | Point mutation, frameshift, insertion, deletion, subsitution |
point mutation (gene mutation) | change of a SINGLE(one) nucleotide, includes: deletion, insertion or substitution of one of the nucleotides |
Frameshift (gene mutation) | Changes the "reading frame"- like changing a a sentence *includes:Insertions, Deletions *proteins builds incorrectly |
deletion (gene mutation) | 1 amino acide is missing from mutant protein |
insertion (gene mutation) | a whole new amino acid is added |
substitution (gene mutation) | when a base pair is substituted and a new codon codes for a different amino acid is used |
what is a genetic disorder? | can be inherited, *a disease or condition that results from mutations that affect the normal functioning of a cell |
3 main types of Genetic Disorders | Autosomal recesssive, Autosomal Dominant, sex-linked |
Autosomal recessive (genetic) | if both parents are heterzygous, the child will have 25% chance of being affected, might not be known |
autsomal dominant (genetic) | trait typically appears in every generation. |
sex-linked (genetic) | Males show the disorder more than female, Son can not inherit disorder from dad. Because males only have one Xchromosome, males are more likely than females to have sex-linked trait that is controlled by recessive alleles |
Cancer | *multiple series of mutations *occurs in replication (DNA) |
Multiple alleles | 3 or more forms a gene that codes for a single trait |
What makes up blood | Red blood cells, White blood cells, Plasma, Platelets |
Red Blood Cells (Erythrocytes) | The most abundant cells in our blood. They produce in the bone marrow. Contain protein called hemoglobin that carries oxygen to our cells |
White Blood Cells (Leukocytes) | They are the part of the immune system and destroys infectious agents called pathogens |
Plasma | This is the yellowish liquid portion of the blood that contains the electrolytes, nutrients and vitamins, hormones, clotting factors and proteins (antibodies) to fight infections |
Platelets (Thrombocytes) | Clotting factors that are carried in the plasma, they clot together in a process called coagulation to seal the wound. |
What are the four blood types | A,B, AB,O- see your card |
universal donor | Blood type O |
Universal Receiver | Blood type AB |
Rh Factor? | The presence of protein or lack of it in the blood RH+- presence of protein RH- no protein |
Blood Transfusion | a procedure in which blood is given to a patient through an intravenous(IV) line in one of the blood vessels |
What is a carrier? | a person who has one recessive allele for a trait and one dominant allele. although they do not have the trait, they can pass the recessive allele on to their offspring |
solve blood type, sex-linked trait and punnet squares | autosomals show different pedigree charts than sex-linked |
Pedigree | a chart showing the genetic connection between two individuals- *genetic family tree |
tell difference between pedigree chart on automsomal recessive and dominant | Rr and RR and rr |
Karyotype | *picture of all of the chromosomes in a cell *arranged as pairs *can reveal if the baby has the correct number of chromosomes and if it is a boy or girl 1-22 Autosome 23- sex chromosomes |
amniocetesis | a sample of the fluids that surrounds the fetus is removed by a large needle |
selective breeding? | Process of selecting and breeding parent organisms to pass on particular traits to the offsprings- two types- inbreeding and hybridzation |
inbreeding | involves crossing 2 individuals that have identical or similar sets of alleles fast horse crossed by fast horse is a fast horse |
hybridization | involves 2 genetically different individuals, with results to bred to have best trait of of both parents- usually breeding dissimilar to parent *corn- resists disease crossed with corn many kernals= corn resist disease and produces many kernals *animal |
advantage of selective breeding to DNA | causes certain alleles to become more common in particular breed |
Genetic Engineering | Genetic splicing-The process in which a sequence of DNA from an organism is first isolated, for a specific trait |
3 steps of Genetic engineering | 1. isolate DNA, 2.Insert DNA in from another organism 3. The new DNA will reproduce and new cells will have the engineered DNA |
what are risk and benefits with genetic engineering? | *Benefit-more food, new medicines, insulin, insect resistant plant with less environmental change. *Con-unknown effects on humans and ecosystem |
Cloning | is a technique that uses technology to make copies of DNA * used to produce organisms with desired traits. (genetically identical to the organism it was produced) |
Dolly and how was she made? | first clone of an adult mammal ever produced 1. removed egg from sheep 2.cell's nucleus was replaced with 6 year old sheep 3.egg placed in 3 sheep uterus 4.5 months later Dolly was born |
DNA fingerprinting | DNA fingerprints is unique to individual, used to identify child's biological dad each band represents a fragment of DNA *examines the bands in the diagram of a gel electroporesis |
Genome | is all the genetic material in organism. most challenging project undertaken |
Blood Type O | Genotype ii |
Blood Type A | Genotype I^AI^A or I^Ai |
Blood type B | Genotype I^BI^B or I^Bi |
Blood Type AB | Geneotype I^AI^B |
hello my name is madison | madison kohl |