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BI 2020 Microbes

Microbiology: P4 Microbial Genetics-Genetic Eng and Gene Therapy

QuestionAnswer
What is the artificial introduction of changes to the genes in a cell? Genetic Engineering
Gene Therapy or Genetic Eng: Deliberate modification of an organism's genetic information by directly changing its genome Genetic Engineering
Gene Therapy or Genetic Eng: The insertion of a normal gene into cells to correct a specific genetic or acquired disorder that is being caused by a defective gene Gene Therapy
What is a novel approach to treat, cure, prevent disease by changing the expression of a person's genes? Gene Therapy
T or F: Gene Therapy is in its infancy and current gene therapy is primarily experimental, with human trials only in the research stages? True
What does Genetic Engineering apply recombinant DNA technology? (1)It is a direct manipulation of an organism's genes by the artificial introduction of a gene into a cell (2)Uses molecular cloning and transformation to alter the structure and function of genes
What is a retrovirus? A virus that stores genetic information in the form of RNA, uses Reverse Transcriptase to incorporate genes into host cell genome
What is the purpose of Genetic Eng? It can allow or genes of interest to be "fixed" to change the protein---restoring function of the cell
How does Gene Therapy cure, treat, or ultimately prevent disease? Inserting normal gene to correct a genetic/acquired disorder that is being caused by defective gene---Changes expression of a person's genes
In what year was the first gene therapy attempted? 1989--Maurice Kuntz
What was the impact of the Jesse Gelsinger case? In 1999 Gene therapy took a major halt, because the study resulted in the unnecessary death of Jesse
Created by: savelae
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