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Stem Cell SIGNALS

HOW STEM CELLS COMMUNICATE

QuestionAnswer
WHY MUST MULTI-CELL ORGANISMS COMMUNICATE? IN ORDER TO COORDINATE THEIR ACTIVITIES SO THE ORGANISM CAN DEVELOP, GROW, REPAIR, ETC
MUST CELLS RECOGNIZE IN/EXTERNAL SIGNALS? YES TO COLLECT AND PROCESS MULTIPLE SIGNALS TO GENERATE PROPER OUTPUT RESPONSE IN ORDER FOR US TO GROW, DEVELOP, DEFEND, REPAIR, REPRODUCE, AND RESPOND T THE ENVIRONMENT EFFECTIVELY.
SIGNAL TRANSDUCTION PROCESS THAT ENABLE CELLS TO RESPOND PROPERLY TO INTERNAL AND EXTERNAL LIGANDS.
SIGNAL TRANSDUCTION PROCESS... 1. RECEPTION 2. TRANDUCTION 3. RESPONSE
MODEL FOR G1 PHASE GO-SIGNAL RECOGNITION CHANGES IN THE PATTERN OF GENE EXPRESSION PRODUCE THE SPECIFIC PROTEINS NECESSARY FOR ASC TO MOVE FROM G1 TO S
KINASES ADD A PHOSPHATE GROUP TO A PROTEIN, THAT CAN TURN ON OR OFF TRANSDUCTION PROTEIN
PHOSPHATASES REMOVE A PHOSPHATE GROUP FROM A PROTEIN, THAT CAN TURN ON OR OFF TRANSDUCTION PROTEIN
PROTEIN KINASE CASCADE SERIES OF KINASE REACTION DURING SIGNAL TRANSD. THAT AMPLIFIES A RECOGNIZED SIGNAL WITHIN CELL TO ENABLE CELL TO RESPOND TO A SMALL NUMBER OF SIGNALS
CYCLIN PROTEINS & CYCLIN DEPENDENT KINASES (CDKs) DETERMINE THE PROGRESS OF THE ASC THROUGH THE CELL CYCLE. IN G1 BOTH PREPARE CELL FOR S PHASE.
CYCLIN PROTEINS BIND TO AND ACTIVATES THE CDKs
WHAT CYCLIN AND CDKs DO IN THE S PHASE? STIMULATE DNA REPLICATION
PROTEASOME... ENTER CYCLIN PROTEIN AND ARE DEGRADED IN A REGULATED MANNER AFTER ASC ENTER NEXT CELL CYCLE PHASE. AMINO ACIDS ALSO EXIT HERE YO BE USED TO MAKE MORE PROTEINS.
Created by: dgira002
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