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Immunobiology

Antigen Capture, Presentation, and Recognition

TermDefinition
Conventional Dendritic Cell majority of DCs example: Langerhan cells: in the skin
Plasmacytoid resemble plasma cells • Present in blood and tissues • Major source of Type 1 interferons in innate immune viral responses.
MHC restriction characteristic of T-lymphocytes that they recognize a foreign peptide antigen only when it is bound to a particular allelic form of MHC
T-cell receptor (TCR) recognizes peptide antigen residues and residues of the MHC of the APC
CCR7 attracts chemokines that direct the DC to exit epithelium and migrate through lymphatic vessels to lymph nodes
Class I is expressed on all nucleated cells
Class II is expressed mainly on DC, macrophages, and B lymphocytes o Also expressed on thymic epithelial cells and endothelial cells o Can be induced on other cell types by cytokine IFN-γ
Created by: 525647468
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